Results 31 to 40 of about 13,428 (198)

Electrochemically Driven Regioselective Radical Functionalization of Allenes: Scope and Mechanistic Insights

Advanced Science, EarlyView.
Allenes emerge as powerful platforms for electrochemical functionalization through radical pathways. Selective radical addition at the central carbon triggers anodic oxidation and intramolecular cyclization, enabling efficient synthesis of oxazolines and oxazolidine‐2‐imines without external oxidants.
Pranjal Pyne, Prateek Saini, Rohel Hoque, Shivam Pandey, Srinivasan Ramakrishnan, Chandra M. R. Volla   +5 more
wiley   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, EarlyView.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

Host–guest interactions in nor-seco-cucurbit[10]uril: novel guest-dependent molecular recognition and stereoisomerism

Beilstein Journal of Organic Chemistry, 2019
The unique monomer and excimer fluorescence emissions of pyrene were first exploited as distinctly photophysical signals to identify the possible diastereomers of guests within nor-seco-cucurbit[10]uril (NS-CB[10]) cavities.
Xiaodong Zhang, Wei Wu, Zhu Tao, Xin-Long Ni   +3 more
doaj   +1 more source

Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides

Redox Biology, 2023
Five out of eight human glutathione peroxidases (GPXs) are selenoproteins, representing proteins that contain selenium as part of the amino acid selenocysteine. The GPXs are important for reducing hydroperoxides in a glutathione-consuming manner and thus
Maria Schwarz, Alina Löser, Qing Cheng, Mareike Wichmann-Costaganna, Patrick Schädel, Oliver Werz, Elias SJ. Arnér, Anna P. Kipp   +7 more
doaj   +1 more source

Supramolecular Terbium‐Threonine Chiral Emitters with Tunable Circularly Polarized Luminescence as Anticounterfeiting‐Ink for Autonomous Data Encryption

Advanced Science, EarlyView.
A one‐pot, aqueous, and scalable method for synthesizing chiral lanthanide supramolecular emitters using terbium and threonine is reported. The aqueous solution of these chiral emitters displays the following features: (i) 100 % transparency, (ii) tunable luminescence and CPL, and (iii) a pH feedback loop that controls the “on‐off” states of ...
P. M. Ajay Sekhar, Nidhin Ravi, Kaloor S. Harikrishnan, Jim Bachmann, Nikos L. Doltsinis, Reji Varghese   +5 more
wiley   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +2 more sources

Taming T-REX: a canonical language for geometry-aware generative design of transition-metal complexes [PDF]

Digital Discovery
Canonical string representations have transformed organic cheminformatics, yet transition-metal complexes (TMCs) lack an equivalent that captures coordination geometry, stereochemistry, and donor topology.
Ilia Kevlishvili, Devmin Dorabawila
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 82, Revision 1 (FGE.82Rev1): Consideration of Epoxides evaluated by the JECFA (65th meeting) [PDF]

EFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

PECULIARITIES OF SEASON BIORHYTHMS IN DIFFERENT PARTS OF FUNCTIONAL SYSTEM MOTHER-PLACENTA-FETUS IN DEPENDENCE ON ITS STEREOFUNCTIONAL ORGANIZATION IN PHYSIOLOGICAL AND COMPLICATED PREGNANCY

Медицинский вестник Юга России, 2013
Purpose: studying seasonal periodicity of stereoisomerism of uteroplacental complex, the dynamics of body weight of infants, studying the chronostructure of mezorhythms of contractive activity of right and left parts of the uterus.Material and Methods ...
N. A. Rogova, T. L. Botasheva, A. V. Chernositov, L. V. Kaushanskaya, E. M. Alexandrova   +4 more
doaj   +1 more source