Results 31 to 40 of about 15,265 (249)
Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
, 2001 Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria +10 more
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Stereoisomerism and Conformational Directionality (Prelog Lecture)
CHIMIA, 1986 The inaugural Prelog Lecture provides me with a unique opportunity to pay tribute to a great scientist, teacher, and friend. As I hope to show, the work of Vladimir Prelog is profoundly relevant to the work that I want to describe today.
Kurt Mislow
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Comptes Rendus. Chimie, 2021 Out-of-plane deformations of metalloporphyrin skeletons have been well documented as playing important roles in relevant biological processes. In contrast, out-of-plane binding to the N-core of large metal cations as period 6 post-transition elements has
Barakat, Wael +5 more
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Computational exploration of the chemical structure space of possible reverse tricarboxylic acid cycle constituents [PDF]
, 2017 The reverse tricarboxylic acid (rTCA) cycle has been explored from various standpoints as an idealized primordial metabolic cycle. Its simplicity and apparent ubiquity in diverse organisms across the tree of life have been used to argue for its antiquity
Fabienne d'Arripe-Longueville +3 more
core +8 more sources
Environment International, 2020 Antibiotic resistance (ABR) is now recognised as a serious global health and economic threat that is most efficiently managed via a ‘one health’ approach incorporating environmental risk assessment.
Felicity C.T. Elder +4 more
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Frontiers in Pharmacology, 2022 The complexity of chemical components of herbal medicines often causes great barriers to toxicity research. In our previous study, we have found the critical divergent hepatotoxic potential of a pair of stilbene isomers in a famous traditional Chinese ...
Juan Liu +12 more
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Angewandte Chemie, EarlyView.This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +2 more sources
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
, 2016 The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
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Analysis of cis-isomer-enriched dihydroquercetin sample by 1D and 2D NMR spectroscopy
Разработка и регистрация лекарственных средствIntroduction. The structure of dihydroquercetin (DHQ) is characterized by two chiral centers at positions 2 and 3 of the benzopyran cycle, resulting in possible diastereomers: trans- and cis-isomers.
R. P. Terekhov +5 more
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Proceedings, 2020 The crystal structures of 4-(3,4-dimethoxyphenylethylamino)-methylidene-2,3,4,10-tetrahydro-1H-pyrido[2,1-b]-quinazolin-10-one (1) and 4-(3,4-methylene-dioxyphenylethylamino)-methylidene-2,3,4,10-tetrahydro-1H-pyrido[2,1-b]-quina-zolin-10-one ...
Akmaljon Tojiboev +7 more
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