Results 21 to 30 of about 13,993 (189)

Friedel-Crafts chemistry. Part 55. Competing indan versus tetralin ring formations during Friedel-Crafts intramolecular cyclialkylations of some selected di-, tri- and tetraphenylated alkanols [PDF]

open access: yesAssiut University Journal of Multidisciplinary Scientific Research, 2018
Friedel-Crafts cyclialkylations of six phenylated alkanols 2a-f to new substituted indans andtetralins mediated by AlCl3/CH3NO2, 85% H2SO4 and/or PPA are described.
doaj   +1 more source

Hepatic Organoid-Based High-Content Imaging Boosts Evaluation of Stereoisomerism-Dependent Hepatotoxicity of Stilbenes in Herbal Medicines

open access: yesFrontiers in Pharmacology, 2022
The complexity of chemical components of herbal medicines often causes great barriers to toxicity research. In our previous study, we have found the critical divergent hepatotoxic potential of a pair of stilbene isomers in a famous traditional Chinese ...
Juan Liu   +12 more
doaj   +1 more source

The influence of stereoisomerism on the biological behavior of 99mTc labeled penicillamine

open access: yes, 2009
The aim of this study is to investigate stereoisomeric behavior of penicillamine and the effect of temperature on labeling. In addition, it was explored how stereoisomerism affected biological behavior of them.
Teksoz S.   +4 more
core   +2 more sources

Analysis of cis-isomer-enriched dihydroquercetin sample by 1D and 2D NMR spectroscopy

open access: yesРазработка и регистрация лекарственных средств
Introduction. The structure of dihydroquercetin (DHQ) is characterized by two chiral centers at positions 2 and 3 of the benzopyran cycle, resulting in possible diastereomers: trans- and cis-isomers.
R. P. Terekhov   +5 more
doaj   +1 more source

THE INFLUENCE OF 5E INSTRUCTIONAL MODEL ON SENIOR HIGH STUDENTS’ PERFORMANCE IN STEREOISOMERISM IN BOLGATANGA AREA, GHANA [PDF]

open access: yes
This study investigated the effectiveness of the 5E instructional model in improving Senior High School students’ performance in stereoisomerism in the Bolgatanga area of Ghana. The study was motivated by persistent poor performance in organic chemistry,
Nyamekye, Kolani   +3 more
core   +1 more source

3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

open access: yesPharmaceuticals
Background: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease with global implications, necessitating effective management strategies.
Tatiana V. Zinevich   +7 more
doaj   +1 more source

Hirshfeld Surface Analysis and Energy Framework for Crystals of Quinazoline Methylidene Bridged Compounds

open access: yesProceedings, 2020
The crystal structures of 4-(3,4-dimethoxyphenylethylamino)-methylidene-2,3,4,10-tetrahydro-1H-pyrido[2,1-b]-quinazolin-10-one (1) and 4-(3,4-methylene-dioxyphenylethylamino)-methylidene-2,3,4,10-tetrahydro-1H-pyrido[2,1-b]-quina-zolin-10-one ...
Akmaljon Tojiboev   +7 more
doaj   +1 more source

Reversible Parahydrogen Induced Hyperpolarization of 15N in Unmodified Amino Acids Unraveled at High Magnetic Field

open access: yesAdvanced Science, 2023
Amino acids (AAs) and ammonia are metabolic markers essential for nitrogen metabolism and cell regulation in both plants and humans. NMR provides interesting opportunities to investigate these metabolic pathways, yet lacks sensitivity, especially in case
Ewoud Vaneeckhaute   +4 more
doaj   +1 more source

A multifaceted review on dihydromyricetin resources, extraction, bioavailability, biotransformation, bioactivities, and food applications with future perspectives to maximize its value [PDF]

open access: yes, 2021
Natural bioactive compounds present a better alternative to prevent and treat chronic diseases owing to their lower toxicity and abundant resources. (+)-Dihydromyricetin (DMY) is a lavanonol, possessing numerous interesting bioactivities with abundant ...
Le, Nguyen Phan Khoi   +11 more
core   +1 more source

Stereodynamics of E/Z isomerization in rotaxanes through mechanical shuttling and covalent bond rotation [PDF]

open access: yes, 2021
We report on a set of rotaxanes with symmetrical axles equipped with a central amide group that installs E/Z stereoisomerism owing to the ring position along the axle. Isomerization by concomitant rotation about the amide bond and ring shuttling along
Baroncini, Massimo   +9 more
core   +1 more source

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