Results 11 to 20 of about 27,712 (197)

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

Radiotherapy for Locally Advanced Pancreatic Adenocarcinoma—A Critical Review of Randomised Trials

Current Oncology, 2023
Pancreatic cancer is rising as one of the leading causes of cancer-related death worldwide. Patients often present with advanced disease, limiting curative treatment options and therefore making management of the disease difficult.
Mathilde Weisz Ejlsmark, Tine Schytte, Uffe Bernchou, Rana Bahij, Britta Weber, Michael Bau Mortensen, Per Pfeiffer   +6 more
doaj   +1 more source

Radiobiological mechanisms of stereotactic body radiation therapy and stereotactic radiation surgery [PDF]

Radiation Oncology Journal, 2015
Despite the increasing use of stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS) in recent years, the biological base of these high-dose hypo-fractionated radiotherapy modalities has been elusive. Given that most human tumors contain radioresistant hypoxic tumor cells, the radiobiological principles for the conventional
Kim, Mi-Sook, Kim, Wonwoo, Park, In Hwan, Kim, Hee Jong, Lee, Eunjin, Jung, Jae-Hoon, Cho, Lawrence Chinsoo, Song, Chang W.   +7 more
openaire   +2 more sources

Lung Stereotactic Body Radiation Therapy (SBRT) dose gradient and PTV volume: a retrospective multi-center analysis

Radiation Oncology, 2019
Background The treatment of lung lesions with stereotactic body radiation therapy calls for highly conformal dose, which is evaluated by a number of metrics. Lung stereotactic body radiation therapy clinical trials constrain a plans gradient index.
David Hoffman, Irena Dragojević, Jeremy Hoisak, David Hoopes, Ryan Manger   +4 more
doaj   +1 more source

CyberKnife Stereotactic Body Radiation Therapy as an Effective Treatment for Hepatocellular Carcinoma Patients With Decompensated Cirrhosis

Frontiers in Oncology, 2020
Purpose: The aim of our study was to evaluate the curative effect and safety of CyberKnife stereotactic body radiation therapy in treating decompensated cirrhosis hepatocellular carcinoma (HCC) patients.Methods: From March 2011 to December 2015, 32 HCC ...
Jing Sun, Aimin Zhang, Wengang Li, Quan Wang, Jia Wang, Yuze Fan, Yingzhe Sun, Dong Li, Dan Zhang, Xuezhang Duan   +9 more
doaj   +1 more source

Stereotactic body radiation therapy for inoperable localized kidney cancer

Сибирский онкологический журнал, 2023
Purpose of the study: to evaluate the overall survival and local control in patients with inoperable kidney cancer treated with stereotactic body radiotherapy (SBRT).Material and Methods. From 2011 to 2021, 42 patients with histologically verified kidney
Zh. E. Sabelnikova, M. M. Sarycheva, E. Ya. Mozerova, A. V. Vazhenin   +3 more
doaj   +1 more source

Treatment of oligometastatic lung cancer with brain metastases using stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT)

Clinical and Translational Radiation Oncology, 2020
Background: There is increasing interest in treating oligometastatic non-small cell lung cancer (NSCLC) patients with stereotactic radiation. We aimed to address whether patients definitively treated with synchronous thoracic stereotactic body radiation ...
John Nikitas, Michael Roach, Cliff Robinson, Jeffrey Bradley, Jiayi Huang, Stephanie Perkins, Christina Tsien, Christopher Abraham   +7 more
doaj   +1 more source

How to integrate stereotactic body radiation therapy and hypofractionation in the management of stage III lung cancer in the age of immunotherapy

Anales del Sistema Sanitario de Navarra, 2020
The constant advances in the field of lung cancer immunotherapy have recently reached the treatment of locally advanced disease with the approval of durvalumab after concurrent chemoradiation.
M. Rico, S. Flamarique Andueza, A. Martín Martínez, M.A. Rodríguez Mendizábal, L. Rosas Gutiérrez, E. Martínez López   +5 more
doaj   +1 more source

A dose falloff gradient study in RapidArc planning of lung stereotactic body radiation therapy

Journal of Medical Physics, 2018
Introduction: Radiation Therapy Oncology Group (RTOG) report #0813 and 0915 recommends using D2cmand R50%as plan quality metrics for evaluation of normal tissue sparing in stereotactic body radiation therapy (SBRT) of lung lesion.
Ganesh Narayanasamy, Dharmin Desai, Sanjay Maraboyina, Jose Penagaricano, Robert Zwicker, Ellis Lee Johnson   +5 more
doaj   +1 more source

Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer

Diagnostics, 2020
Radiation has been relegated to a palliative role in the management of epithelial ovarian cancer (EOC). Contemporary radiation techniques, including intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and image ...
Geraldine Jacobson, Valerie Galvan-Turner   +1 more
doaj   +1 more source