Results 91 to 100 of about 26,281 (176)

AI‐assisted VMAT planning incorporating deep learning‐based dose prediction for head and neck cancer: feasibility of quality standardization and human intervention for irregular cases

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Volumetric‐modulated arc therapy (VMAT) represents a standard of care for head and neck cancer (HNC). However, treatment plan quality depends heavily on the planner's expertise, thereby challenging the standardization of treatment quality.
Seiji Tomori, Kakutaro Narazaki, Shun Tasaka   +2 more
wiley   +1 more source

Online adaptive radiotherapy in stereotactic body radiotherapy for pancreatic cancer patients

Scientific Reports
Stereotactic radiation therapy (SBRT) has emerged as a promising treatment modality for locally advanced pancreatic cancer. The aim of this study is to assess the dosimetric efficacy of online adaptive radiotherapy (ART) in comparison to image-guided ...
Dazhen Jiang, Jin Peng, Hui Xu, Dajiang Wang, Conghua Xie, Xiaoyong Wang, Fuxiang Zhou, Hui Liu   +7 more
doaj   +1 more source

Performance evaluation of a new type of commercial silicon detectors for photon beam dosimetry

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Modern radiotherapy relies on advanced treatment techniques that utilize a large number of small fields, for which maintaining dosimetric accuracy is often challenging. Most vendors have introduced microdetectors suitable for small field dosimetry. Sun Nuclear has developed two silicon diodes with a sensitive volume of 0.35 mm3 that
Indra J. Das, Meisong Ding, George X. Ding   +2 more
wiley   +1 more source

Assessment of 6MV flattening filter free (FFF) beam commissioning parameters for Versa HD and TrueBeam: A comparison study

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Flattening filter‐free (FFF) beams are increasingly deployed for stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS). The Elekta Versa HD (VHD) and Varian TrueBeam (TB) are the two most widely used FFF‐capable platforms; however, no prior study has compared their 6 MV FFF commissioning parameters under fully ...
Mustafa K. Al‐Aseebee, Hussien Mraity, Marco Esposito   +2 more
wiley   +1 more source

Quantitative evaluation of respiratory motion‐induced blurring in expiratory‐phase CBCT for pancreatic SBRT

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Cone‐beam computed tomography (CBCT) is widely used in image‐guided radiotherapy because it reflects the patient's anatomy immediately before treatment. However, CBCT images of the abdominal organs, including the pancreas, are often degraded by respiratory motion.
Airi Nukushina, Ryota Yamada, Takaaki Yoshimura, Norio Katoh, Kentaro Nishioka, Hiroshi Tamura, Masataka Kitagawa, Keiji Kobashi, Takahiro Kanehira, Hidefumi Aoyama, Takayuki Hashimoto   +10 more
wiley   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal, Caden M. Fritson, Alexandra Seas, Heidi Vieira, Surinder K. Batra   +4 more
wiley   +1 more source

Precision Stereotactic Body Radiotherapy for Ultra‐Central NSCLC: Tailored Margins Reduce Toxicity Without Compromising Tumor Control

MedComm, Volume 7, Issue 8, August 2026.
A tailored non‐uniform PTV strategy (including PTVcrop and PTV_high/PTV_low) was used in SBRT for ultra‐central NSCLC to meet stringent OAR constraints. Notably, this SBRT strategy achieved favorable clinical outcomes, with an 84.6% 3‐year local control rate, a median PFS of 42.9 months. Additionally, treatment‐related toxicity was mild, with only 1.5%
Di Liu, Shuangyan Yang, Yun Chen, Ming Liu, Ruifeng Zhao, Minren Hu, Bin Su, QiongYa Wu, Hongyu Wu, Hui Liu, Jinming Yu, Yaping Xu   +11 more
wiley   +1 more source

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

MedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge, Dong Han, Jing Wang, Xinyu Dai, Chen Ma, Feihong Chen   +5 more
wiley   +1 more source

Photon minibeam‐based LATTICE radiotherapy for small and medium‐sized tumors: A dosimetric planning study

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Lattice radiotherapy (LRT) is a spatially fractionated technique that delivers three‐dimensional high‐dose vertices within tumors. However, conventional LRT is constrained by geometric limitations when applied to small and medium‐sized tumor volumes, primarily due to the large beam sizes that restrict optimal lattice pattern ...
Wei Wu, Nimita Shinde, Jiaxin Li, Isabelle Vanhaezebrouck, Kai Jiang, Yuting Lin, Qiang Li, Hao Gao   +7 more
wiley   +1 more source

Translational tumor control probability modeling for NSCLC: A two‐dimensional maximum‐likelihood framework

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Tumor control probability (TCP) modeling for early‐stage non‐small cell lung cancer (NSCLC) is usually performed by one‐dimensional (1D) fitting that assumes error‐free dose and assigns all uncertainty to the local control (LC) axis.
Ryoichi Hinoto, Takeji Sakae, Kenta Takada, Takahisa Eriguchi, Masashi Mizumoto, Atsuya Takeda, Hideyuki Sakurai   +6 more
wiley   +1 more source