Results 81 to 90 of about 30,735 (203)

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source

Dose Prescription Methods in Stereotactic Body Radiotherapy for Small Peripheral Lung Tumors: Approaches Based on the Gross Tumor Volume Are Superior to Prescribing a Dose That Covers 95% of the Planning Target Volume

Technology in Cancer Research & Treatment, 2020
Background and Purpose: We aimed to validate the usefulness of prescriptions based on gross tumor volume for stereotactic body radiotherapy for small peripheral lung tumors.
Takafumi Komiyama MD, PhD, Masahide Saito PhD, Kengo Kuriyama MD, PhD, Kan Marino MD, Shinichi Aoki MD, Ryo Saito MD, Juria Muramatsu MD, Yoshiyasu Maehata MD, PhD, Chen Ze MD, Tomoko Akita MD, Takashi Yamada MD, Naoki Sano PhD, Kazuya Yoshizawa RTT, Ashizawa Kazunari RTT, Suzuki Hidekazu MSc, Koji Ueda RTT, Nam Vu MD, Hiroshi Onishi MD, PhD   +17 more
doaj   +1 more source

Interfraction Anatomical Variability Can Lead to Significantly Increased Rectal Dose for Patients Undergoing Stereotactic Body Radiotherapy for Prostate Cancer [PDF]

, 2017
Stereotactic body radiotherapy for prostate cancer is rapidly growing in popularity. Stereotactic body radiotherapy plans mimic those of high-dose rate brachytherapy, with tight margins and inhomogeneous dose distributions.
Wahl, Michael, Gottschalk, Alexander, Chang, Albert, Shugard, Erin, Descovich, Martina, Roach, Mack, Chen, Josephine, Sudhyadhom, Atchar, Pinnaduwage, Dilini   +8 more
core   +1 more source

Is stereotactic body radiotherapy an effective treatment in metastatic lung cancer with oligoprogressive disease?

, 2023
Oligoprogression (OPD) is defined as a condition where limited progression (1–3 metastases) is observed in patients undergoing systemic cancer treatment.
Michele Aquilano (14776804), Lorenzo Livi (5488322), Nuyttens, Joost J., Luca Visani (8036096), Visani, Luca, Lorenzo Livi, Livi, Lorenzo, Loi, Mauro, Joost J. Nuyttens, Joost J. Nuyttens (6406163), Mauro Loi, Luca Visani, Michele Aquilano, Mauro Loi (8614392), Aquilano, Michele   +14 more
core   +1 more source

A Review of the Australian MRI Linac Program: From Pie in the Sky to Research Milestone

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT The Australian Magnetic Resonance Imaging (MRI) Linear Accelerator program (MRI linac) was a major research project that aimed to build and test a unique MRI linac prototype for cancer treatment. It aimed to improve radiotherapy anatomical targeting and explore physiological targeting. The purpose of this report is to summarise the development
Michael Bernard Barton, Geoffrey Paul Delaney, Peter Greer, Lois Holloway, Peter Metcalfe, Robba Rai, Trang Pham, William S. Price, David Waddington, Stuart Crozier, Paul Keall   +10 more
wiley   +1 more source

Robust Optimization of SBRT Planning for Patients With Early Stage Non-Small Cell Lung Cancer

Technology in Cancer Research & Treatment, 2020
Purpose: Setup uncertainty is a known challenge for stereotactic body radiotherapy planning. Using the internal target volume-based robust optimization was proposed as a more accurate way than the conventional planning target volume-based optimization ...
Haijiao Shang MSc, Yuehu Pu PhD, Yuenan Wang PhD   +2 more
doaj   +1 more source

Lung V5 and Planning Target Volume/Lung Volume Ratio as Independent Risk Factors for ≥Grade 2 Radiation Pneumonitis after Moderately Hypofractionated Radiotherapy: A Retrospective Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung V5 and the planning target volume/lung volume ratio were identified as independent dosimetric risk factors for clinically significant radiation pneumonitis following moderately hypofractionated radiotherapy for lung cancer. Maintaining V5 < 35% may help mitigate this risk in clinical practice.
YuanYou Yang, FengXia Luo, Chao Wang, Gang Ren   +3 more
wiley   +1 more source

Clinical outcomes of stereotactic body radiotherapy for de novo pulmonary tumors in patients with completely resected early stage non-small cell lung cancer

, 2018
Qianqian Zhao, Gang Chen, Luxi Ye, Zhaochong Zeng, Shiming Shi, Jian He Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, China Purpose: Following surgery for early stage non-small-cell lung cancer (NSCLC), de novo ...
Ye L, Shi S, He J, Zhao Q, Chen G, Zeng Z   +5 more
core  

Management of Pulmonary Oligometastases by Stereotactic Body Radiotherapy

, 2014
Aims and Background The aim of the study was to evaluate the feasibility, toxicity and effectiveness of active breathing control-guided stereotactic body radiotherapy in the management of pulmonary oligometastases.
Bahar Dirican, Omer Sager, Ferrat Dincoglan, Serdar Surenkok, Bora Uysal, Hakan Gamsiz, Murat Beyzadeoglu, Kaan Oysul, Selcuk Demiral   +8 more
core   +1 more source

Oligoprogressive renal cell carcinoma: What is the role of surgery?

BJU International, EarlyView.
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re, William H.J. Ince, Leo Bickley, James P. Blackmur, Mouhamad H. Ismail, Justicia Kyeremeh, Teele Kuusk, Eva Mendes Serrao, James O. Jones, Grant D. Stewart   +9 more
wiley   +1 more source