Results 71 to 80 of about 26,281 (176)

Descriptive analysis of screen‐detected versus clinically diagnosed lung cancer cases: evidence of earlier stage shift and treatment differences

Internal Medicine Journal, EarlyView.
Abstract Background Lung cancer is the leading cause of cancer‐related deaths worldwide, largely due to late‐stage diagnosis. Lung cancer screening by computed tomography (CT) reduces mortality by detecting cancers earlier in high‐risk individuals, prompting Australia to launch the National Lung Cancer Screening Program (NLCSP) in 2025.
Jazmin Guayco Sigcha, Tian Mun Chee, Ian A. Yang, Linda Passmore, Kwun M. Fong, Henry M. Marshall   +5 more
wiley   +1 more source

Top 5 Advances in the Last 50 Years: Malignant Gastric and Esophageal Surgery

World Journal of Surgery, EarlyView.
Luís Santos Castro, Lorenzo Ferri
wiley   +1 more source

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

Journal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

Retrospective Analysis of Survival and Adverse Effects Associated With Stereotactic Body Radiation Therapy in 12 Dogs With Hepatocellular Carcinoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT This retrospective analysis evaluated 12 dogs with hepatocellular carcinoma (HCC) who received stereotactic body radiation therapy (SBRT). Dogs received between 6 and 25 Grey (Gy) per fraction for 1–5 fractions for a total dose of 13–30 Gy. Eleven patients (92%) experienced acute adverse effects (AE), with the majority being VRTOG grade 2–3 ...
Victoria Lee Newberry, Mary‐Keara Boss, Del Leary, Tiffany W. Martin   +3 more
wiley   +1 more source

The Definitive‐Intent 10‐Fraction Radiotherapy Protocol (‘The Zurich Protocol’) Yields Lasting Tumour Control and Survival in Dogs With Intracranial Meningiomas

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Moderately hypofractionated definitive‐intent radiotherapy protocols can be used for canine intracranial meningiomas to shorten overall treatment time while maintaining tumour control and limiting normal tissue toxicity. This retrospective study evaluated oncologic outcomes, toxicity, and radiation dose‐volume‐related prognostic factors in ...
Carlotta Ahrens, Sergejs Unterkirhers, Carla Rohrer Bley   +2 more
wiley   +1 more source

Use of the IlluminOss Photodynamic Bone Stabilisation System Following Stereotactic Body Radiation Therapy for Limb‐Sparing in Six Dogs With Presumptive Appendicular Osteosarcoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma is the most common primary bone tumour in dogs, with approximately 75% of cases occurring in the appendicular skeleton. Standard‐of‐care therapy consists of limb amputation followed by carboplatin chemotherapy. A minority of dogs have limb‐sparing treatments including stereotactic body radiation therapy (SBRT) or surgery. SBRT has
Emily A. Pope, Vincent A. Wavreille, Janis L. Lapsley, Eric M. Green, William C. Kisseberth, Robert Rabiner, Laura E. Selmic   +6 more
wiley   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

Head &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan, Avraham Eisbruch, June Corry, Sandra Nuyts, Pim de Graaf, Luiz P. Kowalski, Jonathan J. Beitler, Sweet Ping Ng, William M. Mendenhall, M. P. Sreeram, Karthik N. Rao, Anna Luíza Damaceno Araújo, Alfio Ferlito   +12 more
wiley   +1 more source

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, Volume 48, Issue 9, Page 2570-2583, September 2026.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley   +1 more source

Urethral Metastasis of Therapy‐Induced Neuroendocrine Prostate Cancer Successfully Managed With Chemoradiotherapy: A Case Report

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Urethral metastasis of prostate cancer is exceptionally rare, particularly in castration‐resistant disease. Therapy‐induced neuroendocrine prostate cancer (t‐NEPC) is an aggressive variant with limited treatment options. Case Presentation A 72‐year‐old man, 14 years after diagnosis of prostate adenocarcinoma treated with androgen ...
Toshiaki Kayaba, Satoshi Washino, Takanori Hayase, Kai Yazaki, Kimitoshi Saito, Tomoaki Miyagawa   +5 more
wiley   +1 more source