Results 101 to 110 of about 265,264 (294)

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

Advanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin, Xin Zhang, Zheng Zhao, Chong Cao, Minhua Xu, Suhongrui Zhou, Tian Xuan, Ziyi Jin, Limei Han, Yang Fan, Cong Wang, Xiao Zhu, Ying Mao, Jinhua Yu, Cong Li   +14 more
wiley   +1 more source

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

Advanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao, Xue Zhang, Xiao‐Juan Liu, Yi‐Ling Sun, Cui Yin, Dong‐Liang Tang, Cheng Xiao, Chunyi Zhou   +7 more
wiley   +1 more source

Multidimensional MRI-CT atlas of the naked mole-rat brain

Frontiers in Neuroanatomy, 2013
Naked mole-rats have a variety of distinctive features such as the organisation of a hierarchical society (known as eusociality), extraordinary longevity, and cancer resistance; thus, it would be worthwhile investigating these animals in detail.
Fumiko eSeki, Fumiko eSeki, Keigo eHikishima, Keigo eHikishima, Sanae eNambu, Kazuo eOkanoya, Kazuo eOkanoya, Hirotaka James Okano, Erika eSasaki, Erika eSasaki, Kyoko eMiura, Kyoko eMiura, Hideyuki eOkano, Hideyuki eOkano   +13 more
doaj   +1 more source

Learning the Associations of MITRE ATT&CK Adversarial Techniques [PDF]

arXiv, 2020
The MITRE ATT&CK Framework provides a rich and actionable repository of adversarial tactics, techniques, and procedures (TTP). However, this information would be highly useful for attack diagnosis (i.e., forensics) and mitigation (i.e., intrusion response) if we can reliably construct technique associations that will enable predicting unobserved attack
arxiv  

Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury [PDF]

, 2007
Genetically modified mice represent useful tools for traumatic brain injury (TBI) research and attractive preclinical models for the development of novel therapeutics.
Bayly, Philip V, Brody, David L, Holtzman, David M, Kessens, Chad C, Kim, Eddie, Mac Donald, Christine, Parsadanian, Maia, Schwetye, Katherine E, Spinner, Mike, Yuede, Carla   +9 more
core   +2 more sources

Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain

Advanced Electronic Materials, EarlyView.
In this study, a depth‐adjustable, flexible 3D multi‐shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re‐fabrication.
Minseok Kim, Sehwan Park, Haeyun Lee, Jimin Lee, Namsun Chou, Hyogeun Shin   +5 more
wiley   +1 more source

Image Segmentation by Using Threshold Techniques [PDF]

Journal of Computing, Volume 2, Issue 5, May 2010, 2010
This paper attempts to undertake the study of segmentation image techniques by using five threshold methods as Mean method, P-tile method, Histogram Dependent Technique (HDT), Edge Maximization Technique (EMT) and visual Technique and they are compared with one another so as to choose the best technique for threshold segmentation techniques image ...
arxiv  

A Large-Scale Empirical Comparison of Static and Dynamic Test Case Prioritization Techniques [PDF]

, 2018
The large body of existing research in Test Case Prioritization (TCP) techniques, can be broadly classified into two categories: dynamic techniques (that rely on run-time execution information) and static techniques (that operate directly on source and test code). Absent from this current body of work is a comprehensive study aimed at understanding and
arxiv   +1 more source

The basal ganglia and thalamus of the long-tailed macaque in stereotaxic coordinates. A template atlas based on coronal, sagittal and horizontal brain sections [PDF]

, 2011
A stereotaxic brain atlas of the basal ganglia and thalamus of Macaca fascicularis presented here is designed with a surgical perspective. In this regard, all coordinates have been referenced to a line linking the anterior and posterior commissures (ac ...
A Morel, Alfonso Vázquez, AM Graybiel, C François, DL Rosene, DM Bowden, FA Geneser-Jensen, G Maachi, G Paxinos, G Paxinos, G Paxinos, G Percheron, G Percheron, G Schaltebrand, IA Ilinsky, IA Ilinsky, IA Ilinsky, J Féger, J Olszewski, J Szabo, J Tailarach, JK Mai, José L. Lanciego, K Franklin, KE Krout, KS Saleem, L Puelles, MF Dubach, RF Martin, RF Martin, RF Martin, TR Shanta, V Horsley   +32 more
core   +2 more sources

Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model

Animal Models and Experimental Medicine, EarlyView.
Our study used behavioral tests, laser speckle flowmetry, long‐term potentiation, histochemical staining, molecular experiments, and voxel‐based morphometry to evaluate the hippocampal impairments. It demonstrates early functional and structural impairments in the hippocampus contributing to learning and memory deficits after 1 month of BCAS ...
Ping Tang, Yi Sun, Chunsheng Yang, Nan Zhang   +3 more
wiley   +1 more source