Results 271 to 280 of about 271,466 (344)

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Carbon-iodine atropisomerism on triazole and triazolium frameworks: a breathing axle with divergent adaptivity. [PDF]

Chem Sci
Nambu R, Kikuchi J, Matsumoto A, Yoshikai N.   +3 more
europepmc   +1 more source

Glycocalyx electrostatic potential profile analysis: ion, pH, steric, and charge effects.

, 1989
Schnitzer Je
openalex   +1 more source

Polymer‐in‐Cage Strategy for Pore Tuning of High‐Aspect Ratio ZIF Nanoplate: Toward Sub‐Micrometer‐Thick Large Area CO2 Separation Membranes

Advanced Science, EarlyView.
A “polymer‐in‐cage” strategy transforms a zinc‐acrylate copolymer into an active pore‐modulating agent for ZIF‐8 nanoplates. The polymer actively tunes the MOF's pore structure by anchoring within its windows, while the nanoplates create tortuous pathways.
Minsu Kim, Hyo Jun Min, Min Kyu Choi, Ki Chul Kim, Bomi Kim, Miso Kang, Nahyeon Lee, Kiwon Eum, Jong Hak Kim, Dae Woo Kim   +9 more
wiley   +1 more source

Comparative Review of <i>O</i>,<i>O</i>'-, <i>N</i>,<i>O</i>-, and <i>N</i>,<i>N</i>'-Bidentate Ligands: Structural and Electronic Properties of β-Diketones, Enaminones, and β-Diketiminates. [PDF]

Molecules
Conradie J.
europepmc   +1 more source

Nickel-Catalyzed Intermolecular Cyclization of 2-Bromobenzamide: A General Strategy for Synthesizing 6(5H)-Phenanthridinone Derivatives. [PDF]

Molecules
Xiao X, Zhu X, Shu Y, Zhang B, Zhao C, Nawaz A, Li Z.   +6 more
europepmc   +1 more source

Advancing Torsades de pointes risk prediction: unveiling the role of drug metabolites through molecular docking. [PDF]

Toxicol Res (Camb)
Bilgin E, Tugcu G, Aydin A.
europepmc   +1 more source

London Dispersion Favors <i>Cis</i> Selectivity in the Johnson-Corey-Chaykovsky Epoxidation. [PDF]

J Org Chem
Domanski MHJ, Rummel L, Krug SN, Hausmann H, Solel E, Schreiner PR.   +5 more
europepmc   +1 more source

Design principles for enantiospecific <i>para</i>- and <i>ortho</i>-[3,3] rearrangements of chiral aryl-allyl ethers.

Org Chem Front
Breinsperger J, Kaiser M, Gärtner P.
europepmc   +1 more source