Results 71 to 80 of about 9,364,265 (259)

Role of Steric Effects on Rates of Hydrogen Atom Transfer Reactions

, 2023
The influence of steric effects on the rates of hydrogen atom transfer (HAT) reactions between oxyradicals and alkanes is explored computationally. Quantum chemical density functional theory computations of transition states show that activation barriers
K. N. Houk, Fengjiao Liu (2632246), Jacob N. Sanders, Yi Sun (118759), Yi Sun, K. N. Houk (1247004), Fengjiao Liu, Jacob N. Sanders (5953373)   +7 more
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Steric Effects in Forward and Reverse Menschutkin Reactions of Some Pyridines, Quinolines and Thiazoles

, 1979
The effects of ortho alkyl substituents on the rates of methylation of pyridine and demethylation of N-methylpyridinium iodides are compared (some quinolines are included as 'substituted pyridines').
LW Deady, WL Finlayson, OL Korytsky
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Steric Effects of Alcohols on the [Mn₄O₄] Cubane-Type Structures

Crystals
[M4O4] (M = 3d transition metal) represents an interesting class of compounds featuring cubane-type molecular structures, and particularly, [Mn4O4] cubanes or their derivatives attract much attention by virtue of their potential applications as single ...
Yan He, Zheng Zhou, Haixiang Han
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The Structure and Biogenesis of Nidulin [PDF]

, 1962
The structure of nidulin, the major metabolic product of Aspergillus nidulans, is demonstrated beyond reasonable doubt to be that which was set forth recently by other workers. In support of the structure, a xanthene was isolated and characterized.
Beach, William Frederick
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Investigation into the Influence of Alkyl Thioureas with Varying Steric Hindrance on the Tensile Strength of Electrolytic Copper Foil

Advanced Materials Interfaces
Thiourea derivatives are typical additives that exert different steric hindrance effects on the tensile strength of electrolytic copper foil (ECF). However, the underlying mechanisms remain unclear.
Mingwei Chen, Xing Hu, Jian Huang, Dongmei Wu, Chen Shi, Ning Song, Yuhui Tan, Chao Liu, Yunzhi Tang   +8 more
doaj   +1 more source

Influence of Steric, Electric, and Dielectric Effects on Membrane Potential

, 2008
International audienceThe membrane potential arising through nanofiltration membranes separating two aqueous solutions of the same electrolyte at identical hydrostatic pressures but different concentrations is investigated within the scope of the steric,
Szymczyk, Anthony, Lanteri, Y., Fievet, P., Szymczyk, A.   +3 more
core   +1 more source