Results 11 to 20 of about 23,304 (219)
Conversion of cholesterol injected into man to cholestanol via a 3-ketonic intermediate
Journal of Lipid Research, 1967 Cholesterol-3-3H,4-14C was injected intravenously in man and its transformation to cholestanol was studied. From the 3H:14C ratios in cholestanol isolated from blood, evidence for the participation of a ketonic intermediate in the conversion was obtained.
R.S. Rosenfeld +2 more
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Computational exploration of copper catalyzed vinylogous aerobic oxidation of unsaturated compounds
Scientific Reports, 2021 Selective oxidation is one of the most important and challenging transformations in both academic research and chemical industry. Recently, a highly selective and efficient way to synthesize biologically active γ-hydroxy-α,β-unsaturated molecules from Cu-
Ting Wang +3 more
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Molecules, 2021 In the kidney, prostaglandins formed by cyclooxygenase 1 and 2 (COX-1 and COX-2) play an important role in regulating renal blood flow. In the present study, we report our observations regarding a unique modulatory effect of renal microsomal preparation ...
Hyoung-Woo Bai +4 more
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Molecules, 2023 Neuropathy target esterase (NTE) is a serine hydrolase with phospholipase B activity, which is involved in maintaining the homeostasis of phospholipids. It can be inhibited by aging inhibitors such as some organophosphorus (OP) compounds, which leads to ...
Wenxiong Wu, Pan Wang
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Metabolism of coprostanol-C14 and cholestanol-4-C14 in man
Journal of Lipid Research, 1963 Coprostanol-C14, biosynthetically prepared, was administered orally to two patients, and cholestanol-4-C14 was administered to one of them 10 months later.
R.S. Rosenfeld +2 more
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Cryo‐EM structure of orphan G protein‐coupled receptor GPR21
MedComm, 2023 GPR21 belongs to class A orphan G protein‐coupled receptor (GPCR). The endogenous ligands for human GPR21 remain unidentified. GPR21 expression is associated with developing type 2 diabetes (T2DM), a multifactorial metabolic disease caused by pancreatic ...
Thian‐Sze Wong +8 more
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Clustering psychopathology in male anabolic–androgenic steroid users and nonusing weightlifters
Brain and Behavior, 2023 Introduction Prior research has demonstrated that personality disorders and clinical psychiatric syndromes are common among users of anabolic–androgenic steroids (AAS). However, the prevalence, expression, and severity of psychopathology differ among AAS
Marie Lindvik Jørstad +4 more
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Cancer Treatment and Research Communications, 2021 : Resveratrol (RES), a dietary phenolic compound, was reported to have cancer chemoprotective and chemotherapeutic effects. Earlier we unexpectedly observed that RES has a growth-enhancing effect in some breast cancer cells and can diminish the ...
Masayuki Fukui +3 more
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Cells, 2022 Human type 1 diabetes mellitus is a chronic autoimmune disease characterized by the selective loss of insulin-producing β-cells in pancreatic islets of genetically susceptible individuals.
Bao Ting Zhu
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Esterification of injected epicoprostanol in a human subject
Journal of Lipid Research, 1969 That a necessary requirement for in vivo esterification of 3-hydroxy sterols is the equatorial conformation of the hydroxyl group has been substantiated by the administration of epicoprostanol-3β-3H (3-OH equatorial) to a man with a complete biliary ...
R.S. Rosenfeld, Leon Hellman
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