Results 21 to 30 of about 890,702 (316)

Remote functionalization by tandem radical chain reactions [PDF]

, 1997
Normal radical relay chlorination of cholestan-3α-ol directed by an attached m-iodobenzoate ester group affords a 9α-chloro steroid, but when the same reaction is conducted in the presence of an excess of CBr4 the product is a 9α-bromo steroid ...
Wiedenfeld, David
core   +1 more source

Freedom of Information [PDF]

, 1971
OBJECTIVE: It has previously been shown that a combination of inhaled nitric oxide (iNO) and intravenous (IV) steroid attenuates endotoxin-induced organ damage in a 6-hour porcine endotoxemia model.
Albert, Johanna, Frostell, Claes, Goździk, Waldemar, Göranson, Sofie Paues, Haegerstrand, Caroline Gillis, Harbut, Piotr, Hedenstierna, Göran, Kübler, Andrzej, Ryniak, Stanisław, Zielinski, Stanisław   +9 more
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Metabolism of coprostanol-C14 and cholestanol-4-C14 in man

Journal of Lipid Research, 1963
Coprostanol-C14, biosynthetically prepared, was administered orally to two patients, and cholestanol-4-C14 was administered to one of them 10 months later.
R.S. Rosenfeld, Barnett Zumoff, Leon Hellman   +2 more
doaj   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
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Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies. [PDF]

, 2019
Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects ...
Boerwinkle, Eric, Cheung, Kit Wun Kathy, Chien, Huan-Chieh, Feofanova, Elena V, Giacomini, Kathleen M, Irannejad, Roshanak, Kinchen, Jason M, Stecula, Adrian, Suhre, Karsten, van Borselen, Marjolein, Yee, Sook Wah, Yousri, Noha A, Yu, Bing, Zou, Ling   +13 more
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Mechanism underlying resveratrol’s attenuation of paclitaxel cytotoxicity in human breast cancer cells: Role of the SIRT1-FOXO1-HER3 signaling pathway

Cancer Treatment and Research Communications, 2021
: Resveratrol (RES), a dietary phenolic compound, was reported to have cancer chemoprotective and chemotherapeutic effects. Earlier we unexpectedly observed that RES has a growth-enhancing effect in some breast cancer cells and can diminish the ...
Masayuki Fukui, Hye Joung Choi, Pan Wang, Bao Ting Zhu   +3 more
doaj   +1 more source

Removal of steroid estrogens in carbonaceous and nitrifying activated sludge processes [PDF]

, 2010
This is the post-print version of the final paper published in Chemosphere. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other
Anderson, Baronti, Belfroid, Cao, Carballa, Carballa, Clara, Desbrow, Elise Cartmell, Ewan J. McAdam, Gaulke, Gomes, Gomes, Gomes, Graham, Jobling, John N. Lester, John P. Bagnall, Johnson, Jones, Jones, Joss, Kirk, Koh, Koh, Koh, Kreuzinger, Lai, Lai, Langford, Layton, Liao, Mark D. Scrimshaw, Martin, Martin, Matsui, Purdom, Rittmann, Rodgers-Gray, Simon Pollard, Svenson, Ternes, Tze Y. Chiu, Vader, Yoong K.K. Koh   +44 more
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Pathogenic Mechanism of Autoimmune Diabetes Mellitus in Humans: Potential Role of Streptozotocin-Induced Selective Autoimmunity against Human Islet β-Cells

Cells, 2022
Human type 1 diabetes mellitus is a chronic autoimmune disease characterized by the selective loss of insulin-producing β-cells in pancreatic islets of genetically susceptible individuals.
Bao Ting Zhu
doaj   +1 more source

Clustering psychopathology in male anabolic–androgenic steroid users and nonusing weightlifters

Brain and Behavior, 2023
Introduction Prior research has demonstrated that personality disorders and clinical psychiatric syndromes are common among users of anabolic–androgenic steroids (AAS). However, the prevalence, expression, and severity of psychopathology differ among AAS
Marie Lindvik Jørstad, Morgan Scarth, Svenn Torgersen, Harrison Graham Pope, Astrid Bjørnebekk   +4 more
doaj   +1 more source

Overcoming steroid resistance in T cell acute lymphoblastic leukemia [PDF]

, 2016
In a Perspective, Pieter Van Vlierberghe and Steven Goossens discuss Meijerink and colleagues' findings on steroid resistance in pediatric T cell acute lymphoblastic ...
Goossens, Steven, Van Vlierberghe, Pieter   +1 more
core   +3 more sources