Results 31 to 40 of about 890,702 (316)

Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction [PDF]

open access: yes, 2010
Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance.
Adenuga   +33 more
core   +1 more source

Esterification of injected epicoprostanol in a human subject

open access: yesJournal of Lipid Research, 1969
That a necessary requirement for in vivo esterification of 3-hydroxy sterols is the equatorial conformation of the hydroxyl group has been substantiated by the administration of epicoprostanol-3β-3H (3-OH equatorial) to a man with a complete biliary ...
R.S. Rosenfeld, Leon Hellman
doaj   +1 more source

Spontaneous intracranial hypotension : two steroid-responsive cases [PDF]

open access: yes, 2018
Purpose: Spontaneous intracranial hypotension (SIH) is characterised by orthostatic headache, low cerebrospinal fluid pressure and diffuse pachymeningeal enhancement after intravenous gadolinium contrast administration.
Alexis, Zandolino   +5 more
core   +1 more source

Steroid estrogen determination in sediment and sewage sludge: A critique of chromatographic / mass spectrometry methods incorporating a case study in method development [PDF]

open access: yes, 2004
Current analytical methods for determining steroids in sewage sludge and sediment are reviewed and experimental data comparing LC/MS ESI and GC/MS quantification of extracts from these matrices is presented.
Avcioglu, E   +3 more
core   +1 more source

Rodent Models of Polycystic Ovary Syndrome [PDF]

open access: yes, 2013
Rodents are clearly valuable models for assessing disruption of fertility. The effects of different steroid treatments at different stages of reproductive life through from fetal to adult have been assessed for effects on fertility, ovarian morphology ...
Duncan, Colin, McNeilly, Alan S
core   +1 more source

Strong protection by bazedoxifene against chemically-induced ferroptotic neuronal death in vitro and in vivo

open access: yesCell Communication and Signaling
Ferroptosis, a form of regulated cell death associated with glutathione depletion and excess lipid peroxidation, can be induced in cultured cells by chemicals (e.g., erastin and RSL3).
Xiangyu Hao   +8 more
doaj   +1 more source

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

open access: yes, 2017
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co ...
Indarto, Dono, Izawa, Masao
core  

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka   +7 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Protein disulfide isomerase plays a crucial role in mediating chemically-induced, glutathione depletion-associated hepatocyte injury in vitro and in vivo

open access: yesCell Communication and Signaling
Recently we have shown that protein disulfide isomerase (PDI or PDIA1) is involved in mediating chemically-induced, glutathione (GSH) depletion-associated ferroptotic cell death through NOS activation (dimerization) and NO accumulation. The present study
Yan-Yin Zhu   +4 more
doaj   +1 more source

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