Results 71 to 80 of about 3,508 (215)

Mechanism of action of “cistanche deserticola–Polygala” in treating Alzheimer's disease based on network pharmacology methods and molecular docking analysis

open access: yesIET Systems Biology, Volume 18, Issue 6, Page 271-284, December 2024.
Differential expression of genes between AD patients and the normal population (a) Basic information of GSE5281 dataset. AD patient samples were labelled with green, while control group samples were labelled with purple. (b) Uniform manifold approximation and projection(UMAP) of differentially expressed gene (DEG) in GSE5281. (c) Expression density map
Shaoqiang Wang, Yifan Wang
wiley   +1 more source

Single‐cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease

open access: yesThe Journal of Pathology, Volume 264, Issue 2, Page 212-227, October 2024.
Abstract WT1 encodes a podocyte transcription factor whose variants can cause an untreatable glomerular disease in early childhood. Although WT1 regulates many podocyte genes, it is poorly understood which of them are initiators in disease and how they subsequently influence other cell‐types in the glomerulus.
Jennifer C Chandler   +19 more
wiley   +1 more source

Data from Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, <i>in vitro</i> and <i>in vivo</i> activities, molecular modeling, and protein crystallography

open access: gold, 2023
L. W. Lawrence Woo   +11 more
openalex   +2 more sources

Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17β-HSD1 and/or STS inhibitors

open access: yesBeilstein Journal of Organic Chemistry, 2018
Novel 2- or 4-phosphonated 13α-estrone derivatives were synthesized via the Hirao reaction. Bromo regioisomers (2- or 4-) of 13α-estrone and its 3-benzyl or 3-methyl ether were reacted with diethyl phosphite or diphenylphosphine oxide using Pd(PPh3)4 as ...
Rebeka Jójárt   +7 more
doaj   +1 more source

Low maternal serum estriol as a marker for steroid sulfatase deficiency [PDF]

open access: bronze, 2000
Christine Stanislaw   +3 more
openalex   +1 more source

Steroid Sulfatase Activities in Human Breast Tumors

open access: yesExperimental Biology and Medicine, 1974
SummaryThe ability of human breast tumor preparations to hydrolyze DHEA, estrone, and testosterone sulfates was studied. Of the 85 tumor preparations examined, 31 tumors contained an estrogen sulfatase activity and 19 of which also exhibited sulfatase activity toward DHEA; but there was no testosterone sulfatase in any of the 31 tumor preparations. The
T L, Dao, C, Hayes, P R, Libby
openaire   +2 more sources

Steroidogenic pathway in girls diagnosed with autism spectrum disorders.

open access: yesPLoS ONE
The diagnostic prevalence of autism spectrum disorders (ASD) shows boys to be more affected than girls. Due to this reason, there is a lack of research including and observing ASD girls.
Katarina Jansakova   +8 more
doaj   +1 more source

Supplementary Figure S1 from Steroid Sulfatase Stimulates Intracrine Androgen Synthesis and is a Therapeutic Target for Advanced Prostate Cancer

open access: gold, 2023
Cameron M. Armstrong   +12 more
openalex   +1 more source

Preventive effect of dietary astaxanthin on UVA-induced skin photoaging in hairless mice.

open access: yesPLoS ONE, 2017
Astaxanthin, a carotenoid found mainly in seafood, has potential clinical applications due to its antioxidant activity. In this study, we evaluated the effect of dietary astaxanthin derived from Haematococcus pluvialis on skin photoaging in UVA ...
Toshiyuki Komatsu   +4 more
doaj   +1 more source

Supplementary Table 1 from Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors

open access: gold, 2023
Ryuichiro Sato   +15 more
openalex   +1 more source

Home - About - Disclaimer - Privacy