Results 81 to 90 of about 3,508 (215)

Aldicarb disturbed bile acid, steroid hormone and oxylipin homeostasis in C57BL/6 J mice

open access: yesEcotoxicology and Environmental Safety
Mounting evidence has shown that the gut microbiota plays a key role in human health. The homeostasis of the gut microbiota could be affected by many factors, including environmental chemicals.
Xin Liu   +5 more
doaj   +1 more source

Development of Sulfamoylated 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer. [PDF]

open access: yesJ Med Chem, 2022
Biernacki K   +14 more
europepmc   +1 more source

Dual role of estrogens in endometrial cancer

open access: yesZdravniški Vestnik, 2014
Increased local concentrations of estrogens are a well-known risk factor for endometrial cancer. Estrogens can act as mitogens via the estrogen receptors, and by forming oxidative metabolites they can act as cancer initiators.
Neli Hevir Kene, Tea Lanišnik Rižner
doaj  

Steroid Sulfatase Stimulates Intracrine Androgen Synthesis and is a Therapeutic Target for Advanced Prostate Cancer. [PDF]

open access: yesClin Cancer Res, 2020
Armstrong CM   +12 more
europepmc   +1 more source

MECHANISM OF ACTION OF STEROID HORMONE SULFATASE INHIBITION IN AGING AND NERUODEGENERATIVE DISEASES

open access: yesIBRO Neuroscience Reports, 2023
Manuel Muñoz Ruiz   +5 more
doaj   +1 more source

A Report of Two Cases of Rud Syndrome

open access: yesپزشکی بالینی ابن سینا, 2000
Rud syndrome is a rare disease entity that consists of congenital ichthyosis, mental retardation, hypogonadism, and epilepsy. In this article two cases that are sibling are reported. The parents are relative.
Mohammadreza Derakhshan   +1 more
doaj  

Dysregulation of STS in keratinocytes promotes calcium signaling and differentiation

open access: yesScientific Reports
Steroid sulfatase (STS) is a key enzyme for the desulfation of steroid sulfates, converting them into their biologically active forms. Notably, X-linked ichthyosis (XLI), a genetic disorder characterized by hyperkeratinization, arises as a direct result ...
Tae-Uk Kwon   +4 more
doaj   +1 more source

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