Characterization of Steroid Sulfatase in Human and Mouse Tissues and in the Mouse MC3T3-E1 Pre-Osteoblastic Cell Line [PDF]
Steroid sulfatase cleaves the sulfate group from 3Β-hydroxysteroid sulfates. This enzyme is widely distributed among mammalian tissues, and it has been suggested to play a role in the in situ conversion of inactive steroids to active forms in a variety ...
DiFrancesca, Heidi
core +1 more source
Multiple sulfatase deficiency with neonatal manifestation. [PDF]
Multiple Sulfatase Deficiency (MSD; OMIM 272200) is a rare autosomal recessive inborn error of metabolism caused by mutations in the sulfatase modifying factor 1 gene, encoding the formylglycine-generating enzyme (FGE), and resulting in tissue ...
Ballabio, A.+20 more
core +1 more source
Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou+4 more
wiley +1 more source
Bayesian matching of unlabeled marked point sets using random fields, with an application to molecular alignment [PDF]
Statistical methodology is proposed for comparing unlabeled marked point sets, with an application to aligning steroid molecules in chemoinformatics. Methods from statistical shape analysis are combined with techniques for predicting random fields in spatial statistics in order to define a suitable measure of similarity between two marked point sets ...
arxiv +1 more source
Regulation of Steroid Sulfatase by Glucocorticoids in Human Breast Cancer and Bone Cancer Cell Lines [PDF]
Steroid sulfatase is an enzyme involved in the conversion of active estrogens and androgens from inactive systemic precursors such as estrone sulfate (E1S) and dehydropiandrosterone sulfate (DHEAS).
Barua, Suman
core +1 more source
Identification of diagnostic and therapeutic biomarkers for attention‐deficit/hyperactivity disorder
Abstract Attention‐deficit/hyperactivity disorder (ADHD) is a common psychiatric condition among children and adolescents, often associated with a high risk of psychiatric comorbidities. Currently, ADHD diagnosis relies exclusively on clinical presentation and patient history, underscoring the need for clinically relevant, reliable, and objective ...
Sheng‐Yu Lee+2 more
wiley +1 more source
Roles of steroid sulfatase in brain and other tissues [PDF]
Steroid sulfatase (EC 3.1.6.2) is an important enzyme involved in steroid hormone metabolism. It catalyzes the hydrolysis of steroid sulfates into their unconjugated forms. This action rapidly changes their physiological and biochemical properties, especially in brain and neural tissue.
Marie Bičíková+2 more
openaire +2 more sources
The parasitic weed Striga affects crops such as sorghum, maize, millet, and rice in over 40 countries on the African continent and negatively impacts the livelihood of over 300 million small‐holder farmers. Striga seeds can remain dormant in the soil for many years until they are triggered to germinate by germination stimulants, called strigolactones ...
Mahdere Z. Shimels+5 more
wiley +1 more source
Quantification of Dehydroepiandrosterone, 17β-Estradiol, Testosterone, and Their Sulfates in Mouse Tissues by LC-MS/MS. [PDF]
We report a high-performance, liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) assay to quantify without derivatizaton dehyroepiandrosterone (DHEA), 17β-estradiol (E2), testosterone (T), and their sulfates in serum and tissues.
Napoli, Joseph L, Yoo, Hong Sik
core
Fetal Epidermal Differentiation and Barrier Development In Vivo is Accelerated by Nuclear Hormone Receptor Activators1 [PDF]
Nuclear receptors which interact with the retinoid X receptor are involved in the regulation of epidermal differentiation and development. We have recently shown that activators of the peroxisome proliferator-activated receptor and of the farnesoid X ...
Appel, Renaissance+12 more
core +1 more source