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Heterocyclic steroids. Steroidal pyrimidines [PDF]
Die erste Synthese eines Steroid-Analogen, in welchem Ring A zu einem Pyrimidin umgewandelt wurde, wird beschrieben. Die wichtigste Zwischenstufe 4b wurde durch Abbau von 19-nor-Testosteron gewonnen. Kondensation von 4b mit Thioharnstoff fuhrte zu 17β-Acetoxy-2,4-diazaestr-4-en-1-on-3-thion (5).
D. M. Piatak, E. Caspi
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STEROIDS AND STEROID-LIKE COMPOUNDS [PDF]
Athletes have been searching for an "edge" in competition as long as there has been a reward for success. Anabolic-androgenic steroids have been the most popular of these ergogenic aids when winning is the only goal. The authors present a concise review of these substances, their prevalence, efficacy, adverse effects, and legality.
John A. Lombardo, Jeffrey G. Blue
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Current Opinion in Critical Care, 2002
Corticosteroids are considered to be essential stress hormones. They are secreted together with adrenocorticotropic hormone (ACTH) in response to the pulsatile secretion of corticotropin-releasing hormone from the paraventricular nucleus of the hypothalamus.
Maggy, Riad+3 more
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Corticosteroids are considered to be essential stress hormones. They are secreted together with adrenocorticotropic hormone (ACTH) in response to the pulsatile secretion of corticotropin-releasing hormone from the paraventricular nucleus of the hypothalamus.
Maggy, Riad+3 more
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The Journal of Steroid Biochemistry and Molecular Biology, 1991
Primary aldosteronism is the principal disorder of zona glomerulosa and a number of subsets have been identified: unilateral adenoma; bilateral micro- or macro-nodular hyperplasia (idiopathic aldosteronism); primary hyperplasia and aldosterone-producing carcinoma either adrenal or ectopic. The diagnostic criteria for a correct differential diagnosis of
MANTERO, FRANCO+8 more
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Primary aldosteronism is the principal disorder of zona glomerulosa and a number of subsets have been identified: unilateral adenoma; bilateral micro- or macro-nodular hyperplasia (idiopathic aldosteronism); primary hyperplasia and aldosterone-producing carcinoma either adrenal or ectopic. The diagnostic criteria for a correct differential diagnosis of
MANTERO, FRANCO+8 more
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Steroid structure and steroid activity
British Journal of Dermatology, 1976The diverse biological effects associated with naturally occurring steroids are reviewed, with particular reference to the effect upon biological activity of changes in chemical structure. The motives for synthetic modification of the natural products are discussed and are illustrated by reference to the development of systemic and topical anti ...
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Steroids, steroid receptors and disease
Trends in Molecular Medicine, 2001Abstract The 672nd Biochemical Society meeting was held at Sussex University, UK, from 19 to 21 December 2000. One session was dedicated to the study of steroids and their receptors, and related diseases.
Helen Wiseman, Rosanna Duffy
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