Results 121 to 130 of about 16,062 (239)

Egy ritka, veleszületett neurodegeneratív betegség: a cerebrotendinosus xanthomatosis laboratóriumi diagnosztikája [PDF]

, 2014
Cerebrotendinous xanthomatosis is a rare neurodegenerative disease characterized by the accumulation of cholesterol and cholestanol in the brain and the tendons caused by mutations of the gene encoding sterol 27-hydroxylase (CYP27A1), which is involved ...
Balogh István, Harangi János, Harangi Mariann, Kapás István, Katkó Mónika, Kovács G. Gábor, Madar László, Molnár Mária Judit, Paragh György, Seres Ildikó, Varga Viktória Evelin   +10 more
core   +1 more source

Impact of the sterol 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol on tumor-pathological features, prognosis and response to statin treatment in breast cancer [PDF]

, 2017
Siker Kimbung, Ching‐yi Chang, Pär‐Ola Bendahl, Laura G. Dubois, Will J. Thompson, Donald P. McDonnell, Signe Borgquist   +6 more
openalex   +1 more source

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. [PDF]

, 1994
Ingemar Björkhem, Olof Andersson, Ulf Diczfalusy, B. Sevastik, Ruijuan Xiu, Cunming Duan, Erik Lund   +6 more
openalex   +3 more sources

Expression of key enzymes in bile acid biosynthesis during development: CYP7B1-mediated activities show tissue-specific differences

Journal of Lipid Research, 2002
The developmental variation of cytochrome P450 (CYP)7A1, CYP7B1, CYP27A1, and 3β-hydroxy-Δ5-C27-steroid dehydrogenase, key enzymes in bile acid biosynthesis, were investigated in pigs of different ages.
Maria Norlin
doaj   +1 more source

Cholesterol, Bile Acid, And Lipoprotein Metabolism In Two Strains Of Hamster, One Resistant, The Other Sensitive (LPN) To Sucrose-Induced Cholelithiasis [PDF]

, 2000
A comprehensive study of cholesterol, bile acid, and lipoprotein metabolism was undertaken in two strains of hamster that differed markedly in their response to a sucrose-rich/low fat diet.
Blanchard, Geraldine, Boehler, Nathalie, Combettes-Souverain, Murielle, Eckhardt, Erik, Ferezou, Jacqueline, Lutton, Claude, Milliat, Fabien, Riottot, Michel, Serougne, Colette, Smith, Jeffery L., Souidi, Maamar   +10 more
core  

Human Sterol 27-Hydroxylase (CYP27) Overexpressor Transgenic Mouse Model [PDF]

Journal of Biological Chemistry, 2002
Karen Meir, Daniel Kitsberg, Irit Alkalay, Fanny Szafer, Haim Rosen, Shoshanna Shpitzen, Liat Ben Avi, Bart Staels, Catherine Fievet, Vardiella Meiner, Ingemar Bjo¨rkhem, Eran Leitersdorf   +11 more
openaire   +1 more source

Cerebrotendinous xanthomatosis-a case report with novel compound heterozygous mutation of CYP27A1 gene

Dermatologica Sinica, 2018
Cerebrotendinous xanthomatosis (CTX), a rare autosomal recessive lipid storage disorder which is caused by mutations in gene CYP27A1 leads to deficiency of enzyme sterol 27-hydroxylase.
Jeng Yuan, Pi-Shan Sung, Julia Yu-Yun Lee, Sheau-Chiou Chao   +3 more
doaj   +1 more source

Biosynthesis of the regulatory oxysterol, 5-cholesten-3β,25-diol 3-sulfate, in hepatocytes

Journal of Lipid Research, 2007
Cellular cholesterol homeostasis is maintained through coordinated regulation of cholesterol synthesis, degradation, and secretion. Nuclear receptors for oxygenated cholesterol derivatives (oxysterols) are known to play key roles in the regulation of ...
Xiaobo Li, William M. Pandak, Sandra K. Erickson, Yongjie Ma, Lianhua Yin, Phillip Hylemon, Shunlin Ren   +6 more
doaj   +1 more source

Cafestol, the Cholesterol-Raising Factor in Boiled Coffee, Suppresses Bile Acid Synthesis by Downregulation of Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase in Rat Hepatocytes [PDF]

, 1997
Sabine M. Post, E.C.M. de Wit, P. Hans
openalex   +1 more source

Sterol 27-Hydroxylase– and ApoAI/Phospholipid–Mediated Efflux of Cholesterol From Cholesterol-Laden Macrophages [PDF]

, 1998
J. Westman, Bengt Kallin, Ingemar Björkhem, Jan Nilsson, Ulf Diczfalusy   +4 more
openalex   +1 more source