Results 111 to 120 of about 14,336 (185)

Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function [PDF]

, 2017
It is well established that cholesterol and glycosphingolipids are enriched in the plasma membrane (PM) and form signalling platforms called lipid rafts, essential for T-cell activation and function.
Adlanmerini, Aktas, al Yacoub, Araldi, Ashdown, Balamuth, Bensinger, Bovenga, Brown, Burridge, Chaudhri, Cho, Clark, Daniel, Degroote, Della Torre, Dimeloe, Dunn, Fievet, Foryst-Ludwig, Fox, Gaudet, Gervois, Greenwood, Griffié, Guo, Harris, Herold, Horton, Hughes, Ifergan, Iida, Ikonen, Ishikawa, Ito, Janes, Jeong, Jones, Jury, Jury, Jury, Kanakasabai, Keller, Kidani, Kidani, Kidani, Kirchgessner, Kishimoto, Klein, Kosters, Köberlin, Lappano, Lee, Levental, Levental, Levin, Lingwood, Lisse, Lovett-Racke, Lund, Luquet, Magee, McDonald, Megha, Mesmin, Miguel, Molnár, Nagafuku, Nazarov-Stoica, Ngo, Nuñez, Oliver, Owen, Owen, Pelekanou, Phiel, Quinet, Radhakrishnan, Repa, Rong, Rubin-Delanchy, Sankaran-Walters, Simigdala, Simons, Spann, Steffensen, Sun, Svenson, Swamy, Swinnen, Tang, Tcherepanova, Thangavel, Uppal, Uppal, Varga, Waddington, Waddington, Walcher, Wang, Wang, Wang, Wang, Wang, Wu, Yang, Youssef, Zalba, Zelcer, Zhu   +109 more
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Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. [PDF]

, 2015
Background & aimsAll-trans Retinoic acid (RA) regulates hepatic lipid and bile acid homeostasis. Similar to bile acid (BA), RA accelerates partial hepatectomy (PHx)-induced liver regeneration.
Hu, Ying, Liu, Hui-Xin, Wan, Yu-Jui Yvonne   +2 more
core   +2 more sources

Coordinated regulation of hepatic and adipose tissue transcriptomes by the oral administration of an amino acid mixture simulating the larval saliva of Vespa species [PDF]

, 2016
Genes mapped on Fig. 3.
Akihito Yasuoka, Asuka Kamei, Fumika Shinozaki, Kaori Kondo, Keiko Abe, Kosuke Shimada, Kota Kumagai, Soichi Arai, Takashi Abe, Takashi Kondo, Yuki Watanabe   +10 more
core   +4 more sources

Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice*s⃞

Journal of Lipid Research, 2009
To evaluate the effect of genetic background on high-density lipoprotein cholesterol (HDL) levels in Soat1−/− mice, we backcrossed sterol O-acyltransferase 1 (Soat1)−/− mice, originally reported to have elevated HDL levels, to C57BL/6 mice and ...
Zhiguang Su, Xiaosong Wang, Shirng-Wern Tsaih, Aihong Zhang, Allison Cox, Susan Sheehan, Beverly Paigen   +6 more
doaj   +1 more source

Yeast Gup1(2) proteins are homologues of the Hedgehog Morphogens Acyltransferases HHAT(L): facts and implications [PDF]

, 2016
In multiple tissues, the Hedgehog secreted morphogen activates in the receiving cells a pathway involved in cell fate, proliferation and differentiation in the receiving cells. This pathway is particularly important during embryogenesis. The protein HHAT
Amanai, Chang, Chong, Kumar, Lorenz, Micchelli, Palková, Palková, Roelants, Verduyckt, Zhang, Zhang, Zhang, Zupan   +13 more
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SOAT1 exacerbates tumor progression by promoting YAP signaling activation and attenuating endoplasmic reticulum stress

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Metabolic reprogramming is a hallmark of malignancy, with profound alterations in cellular metabolism driving cancer progression. However, the precise mechanisms by which these metabolic changes promote tumor growth remain poorly understood.
Fan Wang, Qianyu Li, Yifei Qian, Yu Tong, Songling Li, Wenyun Guo, Linfeng Li, Zijun Zhu, Wei‐Qiang Gao, Yanfeng Liu   +9 more
doaj   +1 more source

Review article

, 2019
In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
Hausser, A., von Blume, J.
core   +1 more source

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]

, 2020
BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O, et al,, Meroni, Marica   +2 more
core   +1 more source

Changes in cholesterol metabolism-related gene expression in peripheral blood mononuclear cells from Alzheimer patients [PDF]

, 2012
Background Cholesterol homeostasis dysfunction has been reported to have role in the pathogenesis of Alzheimer disease (AD). Therefore, changes in cholesterol metabolism in blood components may help to develop new potential AD biomarkers.
Antonella Mandas, Claudia Abete, Paolo Putzu, Paolo la Colla, Sandra Dessì, Alessandra Pani   +5 more
core   +2 more sources

Extracellular Vimentin Alters Energy Metabolism And Induces Adipocyte Hypertrophy [PDF]

Diabetes & Metabolism Journal
Background Previous studies have reported that oxidative stress contributes to obesity characterized by adipocyte hypertrophy. However, mechanism has not been studied extensively. In the current study, we evaluated role of extracellular vimentin secreted
Ji-Hae Park, Soyeon Kwon, Young Mi Park
doaj   +1 more source