Results 151 to 160 of about 14,336 (185)

Maternal docosahexaenoic acid and eicosapentaenoic acid supplementation: effects and mechanisms on lipid metabolism in the offspring. [PDF]

Front Nutr
Shao C, Lin H, Yu J, Chen H, Ren Y, Ren J, Zeng Y, Wu Y, Zhang Q, Xiao X.   +9 more
europepmc   +1 more source

Exposure to Tebuconazole Drives Cross-Resistance to Clinical Triazoles in <i>Aspergillus fumigatus</i>. [PDF]

ACS Omega
Meireles LM, Soares FS, de Souza Filho GA, Scherer R.   +3 more
europepmc   +1 more source

The Multilayered Landscape of Ferroptosis: Plasticity, Propagation, and Evolutionary Perspectives. [PDF]

Antioxidants (Basel)
Chen H, Yan H, Bu H, Ye F.
europepmc   +1 more source

Avasimibe Abolishes the Efficacy of Fluvastatin for the Prevention of Cancer in a Spontaneous Mouse Model of Breast Cancer. [PDF]

Int J Mol Sci
Bhardwaj A, Koh A, Bhala R, Sandhu J, Ju Z, Cando LF, Wang J, Bedrosian I.   +7 more
europepmc   +1 more source

Ferroptosis: biology and role in liver disease. [PDF]

J Gastroenterol
Hino K, Nishina S, Yanatori I.
europepmc   +1 more source

Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review). [PDF]

Int J Mol Med
He Z, Zhang L, Gong S, Yang X, Xu G.
europepmc   +1 more source

Organelle-specific regulation of ferroptosis. [PDF]

Biol Direct
Zhang Y, Liu M, Li M, Wu Y, Xie M, Liu X, Lu H, Zhai X, Yang Y.   +8 more
europepmc   +1 more source

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Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer

Prostaglandins & Other Lipid Mediators, 2021
Prostate cancer (PCa) is one of the most fatal malignant tumors that occurs in the prostate epithelium, especially in older men, the mortality of which ranks sixth among all cancer-related deaths. It has been urgently needed to elucidate the pathogenesis of PCa and provide promising therapeutic targets for PCa treatment. The Sterol O-acyltransferase 1 (
Yuan, Liu, Yeqiang, Wang, Sida, Hao, Yong, Qin, Yuye, Wu   +4 more
openaire   +2 more sources

A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma

Investigational New Drugs, 2020
Background Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with very limited treatment options. Nevanimibe HCl (formerly ATR-101), a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, has been shown in nonclinical studies to decrease adrenal steroidogenesis at lower doses and to cause apoptosis of adrenocortical ...
David C, Smith, Matthias, Kroiss, Electron, Kebebew, Mouhammed Amir, Habra, Rashmi, Chugh, Bryan J, Schneider, Martin, Fassnacht, Pegah, Jafarinasabian, M Marian, Ijzerman, Vivian H, Lin, Pharis, Mohideen, Aung, Naing   +11 more
openaire   +2 more sources