Results 81 to 90 of about 14,312 (191)
Zhongguo linchuang yanjiu"Objective To investigate the mRNA expression levels of sterol O⁃acyltransferase 1（SOAT1）and triggering receptor expressed on myeloid cells 1（TREM1）in esophageal squamous cell carcinoma（ESCC）tissues and analyze their associations with clinical ...
LU Yang，GAO Chao
doaj +1 more source
Targeting hepatic glycerolipid synthesis and turnover to treat fatty liver disease [PDF]
, 2014 Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of metabolic abnormalities ranging from simple hepatic steatosis (accumulation of neutral lipid) to development of steatotic lesions, steatohepatitis, and cirrhosis.
Finck, Brian N, Schweitzer, George G
core +3 more sources
Mechanisms of lipid malabsorption in Cystic Fibrosis: the impact of essential fatty acids deficiency [PDF]
, 2005 Affiliation: CHU-Sainte-Justine, Université de MontréalTransport mechanisms, whereby alimentary lipids are digested and packaged into small emulsion particles that enter intestinal cells to be translocated to the plasma in the form of chylomicrons, are ...
Drouin, Éric +3 more
core +2 more sources
Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li +6 more
wiley +1 more source
Alteration of gene expression in mammary gland tissue of dairy cows in response to dietary unsaturated fatty acids [PDF]
, 2011 The aim of this study was to determine the effects of supplementing unprotected dietary unsaturated fatty acids (UFAs) from different plant oils on gene expression in the mammary gland of grazing dairy cows.
Baal, J., van +4 more
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Food Frontiers, Volume 7, Issue 2, March 2026.ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
Communications BiologyWolfiporia cocos is a medicinal mushroom used in China. It biosynthesizes pachymic acid (PA), a main therapeutic triterpene associated with therapies. Nowadays, the unknown PA biosynthesis leads to difficulties in increasing its content in W.
Heping Liu +13 more
doaj +1 more source
HepatologyBackground and Aims: The development of hepatocellular carcinoma (HCC) is intricately linked to metabolic processes and immune evasion strategies. As an emerging metabolic vulnerability in HCC, the detailed molecular mechanisms of sterol O-acyltransferase 1 (SOAT1) and its role in immune regulation remain ...
Huanhuan Ma +12 more
openaire +1 more source
Sterol regulatory element-binding proteins are regulators of the rat thyroid peroxidase gene in thyroid cells [PDF]
, 2009 Sterol regulatory element-binding proteins (SREBPs)-1c and -2, which were initially discovered as master transcriptional regulators of lipid biosynthesis and uptake, were recently identified as novel transcriptional regulators of the sodium-iodide ...
Rauer, Christine +4 more
core +1 more source
iMetaOmics, Volume 3, Issue 1, March 2026.First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang +9 more
wiley +1 more source