Results 71 to 80 of about 115,811 (342)

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

Advanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu, Huiyuan Ma, Tinghui Zhu, Shuwei Huang, Manxi Lu, Qiong Wang, Zai‐Long Chi   +6 more
wiley   +1 more source

Maintaining heart health [PDF]

, 2013
Risk factors for heart disease are wide ranging and cumulative.
Kime, NH
core  

Cultivar and Year-to-Year Variation of Phytosterol Content in Rye (Secale cereale L.) [PDF]

, 2004
Intake of phytosterols (and -stanols) has been shown to decrease the level of low-density lipoprotein cholesterol and thus protect against development of cardiovascular diseases.
Hansen, H.B., Hellgren, L.I., Jørgensen, J.R., Zangenberg, M.   +3 more
core   +1 more source

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

Structural basis for plant plasma membrane protein dynamics and organization into functional nanodomains

eLife, 2017
Plasma Membrane is the primary structure for adjusting to ever changing conditions. PM sub-compartmentalization in domains is thought to orchestrate signaling. Yet, mechanisms governing membrane organization are mostly uncharacterized. The plant-specific
Julien Gronnier, Jean-Marc Crowet, Birgit Habenstein, Mehmet Nail Nasir, Vincent Bayle, Eric Hosy, Matthieu Pierre Platre, Paul Gouguet, Sylvain Raffaele, Denis Martinez, Axelle Grelard, Antoine Loquet, Françoise Simon-Plas, Patricia Gerbeau-Pissot, Christophe Der, Emmanuelle M Bayer, Yvon Jaillais, Magali Deleu, Véronique Germain, Laurence Lins, Sébastien Mongrand   +20 more
doaj   +1 more source

Sterol content in sunflower seeds (Helianthus annuus L.) as affected by genotypes and environmental conditions [PDF]

, 2010
Phytosterols play essential roles in many plant cell mechanisms. They are of industrial interest since, as part of the diet, they can reduce Low Density Lipoprotein cholesterol.
Alignan, Marion, Bouniols, Andrée, Cerny, Muriel, Merah, Othmane, Mouloungui, Zéphirin, Roche, Jane, Vear, Felicity   +6 more
core   +3 more sources

Rational Design of Ni3+‐Rich Nickel Nitride Enables Paired Electrooxidation of Sterol and Hydrogen Evolution in a Flow Electrolyzer

Advanced Science, EarlyView.
The rational design of Ni3+‐rich active sites on nickel nitride nanosheets via Pd‐induced electronic modulation, which was employed in the electrooxidation of sterol coupled with H2 production in a large flow electrolyzer. This work offers a novel strategy for the design and synthesis of highly efficient electrocatalysts and electrolyzers toward the ...
Suiqin Li, Jieyu Wang, Ge Feng, Jiahui He, Kai Li, Lihao Liu, Yuhang Wang, Zixian Jia, Yanfei Xu, Wenwu Zhong, Xing Zhong, Jianguo Wang   +11 more
wiley   +1 more source

Microbial community dynamics during composting of sewage sludge and straw studied through phospholipid and neutral lipid analysis [PDF]

, 2008
The composting process involves a succession of different communities of microorganisms that decompose the initial material, transforming it into a stable final product. In thiswork, the levels of phospholipid fatty acid (PLFA), neutral lipid fatty acid (
Amir, Soumia, Hafidi, Mohamed, Merlina, Georges, Pinelli, Eric, Revel, Jean-Claude, Winterton, Peter   +5 more
core   +3 more sources

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Lateral transfer of tetrahymanol-synthesizing genes has allowed multiple diverse eukaryote lineages to independently adapt to environments without oxygen

Biology Direct, 2012
Sterols are key components of eukaryotic cellular membranes that are synthesized by multi-enzyme pathways that require molecular oxygen. Because prokaryotes fundamentally lack sterols, it is unclear how the vast diversity of bacterivorous eukaryotes that
Takishita Kiyotaka, Chikaraishi Yoshito, Leger Michelle M, Kim Eunsoo, Yabuki Akinori, Ohkouchi Naohiko, Roger Andrew J   +6 more
doaj   +1 more source