Results 11 to 20 of about 6,337 (246)

Redesign and reconstruction of a steviol-biosynthetic pathway for enhanced production of steviol in Escherichia coli [PDF]

open access: yesMicrobial Cell Factories, 2020
Background Steviol glycosides such as stevioside have attracted the attention of the food and beverage industry. Recently, efforts were made to produce these natural sweeteners in microorganisms using metabolic engineering. Nonetheless, the steviol titer
Jun Ho Moon   +3 more
doaj   +3 more sources

Molecular basis for branched steviol glucoside biosynthesis [PDF]

open access: greenProceedings of the National Academy of Sciences, 2019
Steviol glucosides, such as stevioside and rebaudioside A, are natural products roughly 200-fold sweeter than sugar and are used as natural, noncaloric sweeteners. Biosynthesis of rebaudioside A, and other related stevia glucosides, involves formation of the steviol diterpenoid followed by a series of glycosylations catalyzed by uridine ...
Soon Goo Lee   +3 more
openalex   +4 more sources

Steviol, the aglycon of steviol glycosides, does not reduce hyperglycemia in mice with type 2 diabetes

open access: yesPhytomedicine Plus, 2022
Background: Steviol glycosides, constituents of Stevia rebaudiana Bertoni, are high-intensity sweeteners that enhance glucose-induced insulin secretion and decrease hyperglycemia in mice and rats.
Caroline Simoens   +9 more
doaj   +1 more source

Bioconversion of steviol glycosides into steviol by Microbacterium barkeri [PDF]

open access: yesJournal of Asian Natural Products Research, 2020
The strain which degraded steviol glycosides to steviol (STE) was screened and isolated from soil samples. A phylogenetic tree was constructed and used to determine the taxonomic status of the strain. 16S rDNA sequence was ultimately used to identify the strain as Microbacterium barkeri XJ.
Jiang, Hui-Ling   +8 more
openaire   +3 more sources

Safety evaluation of glucosylated steviol glycosides as a food additive in different food categories

open access: yesEFSA Journal, 2022
The EFSA Panel on Food Additive and Flavourings (FAF) assessed the safety of glucosylated steviol glycosides proposed for use as a new food additive in different food categories.
EFSA Panel on Food Additives and Flavourings (FAF)   +27 more
doaj   +1 more source

Steviol reduces MDCK Cyst formation and growth by inhibiting CFTR channel activity and promoting proteasome-mediated CFTR degradation. [PDF]

open access: yesPLoS ONE, 2013
Cyst enlargement in polycystic kidney disease (PKD) involves cAMP-activated proliferation of cyst-lining epithelial cells and transepithelial fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR) chloride ...
Chaowalit Yuajit   +5 more
doaj   +1 more source

Validation of an HPLC Method for Pretreatment of Steviol Glycosides in Fermented Milk

open access: yesFoods, 2021
Steviol glycosides are used in food and beverages worldwide as natural sweeteners, serving as a low-calorie sugar substitute. The acceptable daily intake of steviol is 0–4 mg/kg body weight. The rising demand for dairy products has led to a corresponding
Jin-Man Kim, Jong-Ho Koh, Jung-Min Park
doaj   +1 more source

Efficient Bioconversion of Stevioside and Rebaudioside A to Glucosylated Steviol Glycosides Using an Alkalihalobacillus oshimesis-Derived Cyclodextrin Glucanotransferase

open access: yesMolecules, 2023
The enzymatic transglycosylation of steviol glycosides can improve the edulcorant quality of steviol glycosides. Cyclodextrin glucanotransferase (CGTase) is one of the most popular glucanotransferases applied in this reaction.
Ruiqin Zhang   +6 more
doaj   +1 more source

Engineering of cyclodextrin glycosyltransferase improves the conversion efficiency of rebaudioside A to glucosylated steviol glycosides and increases the content of short-chain glycosylated steviol glycoside

open access: yesMicrobial Cell Factories, 2023
Background Compared with steviol glycosides, the taste of glucosylated steviol glycosides is better and more similar to that of sucrose. At present, cyclodextrin glucanotransferase (CGTase) is primarily used to catalyze the conversion of steviol ...
Ruiqin Zhang   +7 more
doaj   +1 more source

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