Results 21 to 30 of about 6,337 (246)

Steviol Represses Glucose Metabolism and Translation Initiation in Pancreatic Cancer Cells

Biomedicines, 2021
Pancreatic cancer has the worst prognosis and lowest survival rate among all cancers. Pancreatic cancer cells are highly metabolically active and typically reprogrammed for aberrant glucose metabolism; thus they respond poorly to therapeutic modalities ...
Sonam Kumari, Mohammed Sikander, Shabnam Malik, Manish K. Tripathi, Bilal B. Hafeez, Murali M. Yallapu, Subhash C. Chauhan, Sheema Khan, Meena Jaggi   +8 more
doaj   +1 more source

Stool and Plasma Metabolites and Cognitive Function in the Boston Puerto Rican Health Study [PDF]

Alzheimers Dement
Abstract Background Several studies have reported alterations in the gut microbiome and plasma metabolome in dementia, but no studies have concurrently examined metabolites in stool and plasma. Evidence is especially lacking in Latinos/Hispanics who have unique metabolic and microbiome profiles and are at an increased risk of dementia.
Dinesh D, Kuntz T, Morgan X, Scott T, Garelnabi M, Tucker K, Huttenhower C, Palacios N.   +7 more
europepmc   +2 more sources

Glucosylation of Steviol and Steviol-Glucosides in Extracts from Stevia rebaudiana Bertoni [PDF]

Plant Physiology, 1991
To evaluate and characterize stevioside biosynthetic pathway in Stevia rebaudiana Bertoni cv Houten, two enzyme fractions that catalyze glucosylation of steviol (ent-13-hydroxy kaur-16-en-19-oic acid) and steviol-glucosides (steviol-13-O-glucopyranoside, steviolbioside and stevioside), utilizing UDP-glucose as the glucose donor, were prepared from the ...
H, Shibata, S, Sonoke, H, Ochiai, H, Nishihashi, M, Yamada   +4 more
openaire   +2 more sources

Safety of a proposed amendment of the specifications for steviol glycosides (E 960) as a food additive: to expand the list of steviol glycosides to all those identified in the leaves of Stevia Rebaudiana Bertoni

EFSA Journal, 2020
The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of the proposed amendment of the specifications for steviol glycosides (E 960) as a food additive, in particular to expand the list of steviol glycosides ...
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Rainer Gürtler, Ursula Gundert‐Remy, Trine Husøy, Melania Manco, Wim Mennes, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Detlef Wölfle, Matthew Wright, Gisela Degen, Alessandra Giarola, Ana M Rincon, Laurence Castle   +21 more
doaj   +1 more source

An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae [PDF]

, 2017
Corynebacterium diphtheriae (Cd) is a Gram-positive human pathogen responsible for diphtheria infection and once regarded for high mortalities worldwide.
Azevedo, Vasco A.C., Barh, Debmalya, Baumbach, Jan, Benevides, Leandro de Jesus, Costa, Daniela Arruda, Ghosh, Preetam, Hassan, Syed Shah, Jamal, Syed Babar, Röttger, Richard, Silva, Artur, Tiwari, Sandeep, Turjanski, Adrián G., Ullah, Asad, Viana, Marcus V.   +13 more
core   +6 more sources

Stereoselective Synthesis and Antiproliferative Activity of Steviol-Based Diterpene 1,3-Aminoalcohol Regioisomers

Molecules, 2023
A series of novel diterpene-type 1,3-aminoalcohols and their regioisomers have been synthesised from natural stevioside in a stereoselective manner.
Dorottya Bai, Zsuzsanna Schelz, Mária Fanni Boncz, István Zupkó, Zsolt Szakonyi   +4 more
doaj   +1 more source

Microbial Degradation of Steviol derived from steviol glycosides [PDF]

, 2013
As well as from Paraguayan soil samples of a stevia plantation as from samples of Belgian soils that never had contact with stevia or steviol glycosides bacterial consortia were derived that hydrolysed steviol glycosides to steviol. This activity was not influenced by heating (20 min. 80 °C) or boiling (10 min. 100 °C) the soil samples.
Etienne Jooken, Ruis Amery, Annick Monballiu, Nico Moons, Wim M. De Borggraeve, Wim Dehaen, Boudewijn Meesschaert   +6 more
openalex   +2 more sources

Characterization of Microbial Degradation Products of Steviol Glycosides

Molecules, 2021
Steviol glycosides were subjected to bacteria present in a soil sample collected from a Stevia plantation in Paraguay. During the incubation experiments, next to the aglycon steviol, steviol degradation products were also formed.
Gert Steurs, Nico Moons, Luc Van Meervelt, Boudewijn Meesschaert, Wim Michel De Borggraeve   +4 more
doaj   +1 more source

Dynamics of steviol glycosides (stevioside and rebaudioside-A) with growth and development of Stevia rebaudiana Bertoni [PDF]

, 2016
In the present investigation, the dynamics of steviol glycosides (stevioside and rebaudioside-A) of Stevia rebaudiana with their growth stages were studied. The study aimed to examine the best stage of harvesting (month of the year) the crop with respect
Kumar, Suresh, Kumari, Neena, Rana, R. C., Sharma, Y. P.   +3 more
core   +2 more sources

Evaluation of Steviol Injection on Chicken Embryos: Effects on Post-hatch Development, Proportional Organ Weights, Plasma Thyroid Hormones and Metabolites

The Journal of Poultry Science, 2010
At day 7 of incubation, eggs were injected with high levels of steviol (1.5 and 3mg per egg). At hatch, no effect of steviol injection was observed on plasma thyroid hormone levels, hatchability, body weight and chick quality. Proportional liver weight
Mohsen Daneshyar, Jan M.C. Geuns, Johan G. Buyse, Hassan Kermanshahi, Hilke Willemsen, Zarbakht Ansari, Eddy Decuypere, Nadia Everaert   +7 more
doaj   +1 more source