Results 51 to 60 of about 20,141 (153)
Introducción: Las estrategias vacunales para potenciar respuestas de linfocitos T CD8+ citotóxicos (CTL) constituyen un reto debido a la necesidad de favorecer la presentación cruzada de antígenos (Ag) exógenos por las células presentadoras de antígenos (
María Eliana Lanio Ruiz +9 more
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A new Cytolysin, termed as Gigantoxin-4, was isolated from the sea anemone Stichodactyla gigantea and found to be highly homologous with Cytolysin-3 (HMg III) from Heteractis magnifica, RTX-A from Radianthus macrodactylus, and Sticholysin-1 (St I) and ...
Bo Hu, Wei Guo, Liang-hua Wang, Jian-guang Wang, Xiao-yu Liu, Bing-hua Jiao
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Kinetics and mechanism of st i modification by peroxyl radicals [PDF]
St I is a toxin present in the Caribbean Sea anemone Stichodactyla helianthus which is highly hemolytic in the nanomolar concentration range. Exposure of the toxin to free radicals produced in the pyrolysis of 2,2′ -azobis(2-amidinopropane) hydrochloride
Lanio, M. E. +8 more
core +3 more sources
Mechanism of the leakage induced on lipid model membranes by the hemolytic protein sticholysin II from the sea anemone Stichodactyla helianthus [PDF]
A potent hemolytic polypeptide, sticholysin II, has been purified to homogeneity from the sea anemone Stichodactyla helianthus. The protein produces leakage of aqueous contents of model lipid vesicles composed of either phosphatidylcholine or sphingomyelin if cholesterol is present in these membranes.
V, de los Rios +4 more
openaire +2 more sources
Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Químicas, leída el 18/06/2021The usefulness of toxicity across the tree of life is far beyond doubt. Most, if not all, organisms produce compounds that can be used for attack and/
Palacios Ortega, Juan
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Self-homodimerization of an actinoporin by disulfide bridging reveals implications for their structure and pore formation [PDF]
The Trp111 to Cys mutant of sticholysin I, an actinoporin from Stichodactyla helianthus sea anemone, forms a homodimer via a disulfide bridge. The purified dimer is 193 times less hemolytic than the monomer.
Hervis, Yadira De La Patria +21 more
core +1 more source
Insights on the structure-activity relationship of peptides derived from Sticholysin II.
Sticholysin II (StII) is a pore-forming actinoporin from the sea anemone Stichodactyla helianthus. A mechanistic model of its action has been proposed: proteins bind to cell membrane, insert their N-termini into the lipid core and assemble into homo ...
Pertinhez TA +8 more
core +2 more sources
Application of stichodactyla toxin in the treatment of autoimmune diseases
Stichodactyla helianthus (Ellis, 1768) je vrsta vlasulje prisutna u Karipskom moru. Sadrži neurotoksine koji prvenstveno služe za obranu od predatora. Proučavanje peptida ShK iz ove vrste pokazalo je da osim toksičnog učinka postoji i moguća terapeutska ...
Bovan, Srećko
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Efeitos do extrato bruto da anêmona do mar Bunodosoma caissarum sobre o comportamento e o sistema glutamatérgico em camundongos / [PDF]
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências ...
Silva, Margarete Gondran Carvalho da
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We have investigated the relationship between the status of red blood cells (RBCs) and their susceptibility to toxin sticholysin II (StII) hemolytic activity; we have evaluated this effect in different RBC ensembles, comprising young and old cells, and in cells partially damaged by their pre-exposition to a free radical source.
Celedon, Gloria +9 more
openaire +4 more sources

