Results 161 to 170 of about 163,843 (288)

Stiff systems

Scholarpedia, 2007
Lawrence F. Shampine, Skip Thompson
openaire   +2 more sources

Integration of Stiff Equations [PDF]

Proceedings of the National Academy of Sciences, 1952
Curtiss, C. F., Hirschfelder, J. O.
openaire   +2 more sources

Utility of endoscopic ultrasonography elastography as a predictive tool for post-treatment recurrence of resectable pancreatic cancer treated with neoadjuvant and adjuvant chemotherapy: a retrospective study in Japan. [PDF]

Clin Endosc
Kano Y, Ishikawa T, Yamao K, Mizutani Y, Iida T, Takada Y, Yamamura T, Furukawa K, Kawashima H.   +8 more
europepmc   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Target FADS1-arachidonic acid-ferroptosis axis: A metabolic bridge linking matrix stiffness to PDAC stemness. [PDF]

Mater Today Bio
Gong T, Yan J, Zhu H, Guan X, Xing H, Wang Z, Wu D, Zhu B, Zhang X, Ma Y.   +9 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Stiff competition [PDF]

Nature, 2018
openaire   +2 more sources

Mechanosensitive phosphorylation of NFATC4 at S213/S217 drives fibroblast-to-myofibroblast transition and fibrosis. [PDF]

J Clin Invest
Kadri S, Mattner LF, Zeng Z, Prakki SRS, Verma AK, Cetin U, Mayr CH, Ansari M, Wei X, Asgharpour S, Wasik AA, Kneidinger N, Stoleriu MG, Behr J, Polleux J, Yildirim AÖ, De Sadeleer LJ, Wuyts WA, Burgstaller G, Mann M, Mück-Häusl M, Schiller HB.   +21 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Engineering a biomimetic multiphasic suture anchor system for enhanced rotator cuff enthesis regeneration. [PDF]

Sci Adv
Li Z, Lee SH, Xu L, Santos M, Lu R, Zhang EY, Kim DH, Tumenbayar BI, Blanch TE, Jung J, Shin J, Bae Y, Tran RT, Schaer T, Heo SC.   +14 more
europepmc   +1 more source