Results 231 to 240 of about 163,843 (288)

Guidewire-Induced Pseudostenosis of the Iliac Artery During Chronic Total Occlusion Percutaneous Coronary Intervention. [PDF]

JACC Case Rep
Patel A, Yamasaki H, Daher E.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Mechanical Stiffening Promotes Growth, Invasion-Associated Phenotypes, and Reduced Selumetinib Sensitivity in 3D Plexiform Neurofibroma Cultures. [PDF]

Cells
Ji K, Shi C, Zhang J, Mattingly RR.
europepmc   +1 more source

Matrix Stiffness Directs Stemness Signatures in Breast Cancer. [PDF]

Adv Healthc Mater
Kopecky C, Pandzic E, Porazinski S, Gooding JJ, Kilian KA.   +4 more
europepmc   +1 more source

Semi-quantitative assessment of paraspinal muscle fat infiltration in single-level C5-6 cervical spondylosis using gray-level thresholding on conventional MRI: associations with disc degeneration and posture-related segmental angular change. [PDF]

Front Med (Lausanne)
Li Y, Zhao L, Zhang W, Ge X, Lu H, Shi H, Yu H.   +6 more
europepmc   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells. [PDF]

Adv Sci (Weinh)
Younesi FS, Miller AE, Diao L, Guo X, Andonian N, Karimizadeh E, Barker TH, Hinz B.   +7 more
europepmc   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage-Adaptive Bone Regeneration. [PDF]

Adv Sci (Weinh)
Yang Y, Yang F, Wang L, Li Z, Li W, Zhang X.   +5 more
europepmc   +1 more source

Correction to "Synergistic Effects of Matrix Biophysical Properties on Gastric Cancer Cell Behavior via Integrin-Mediated Cell-ECM Interactions". [PDF]

Small
europepmc   +1 more source

Glaucoma – ‘A Stiff Eye in a Stiff Body’

Current Eye Research, 2022
Glaucoma is a progressive, age-related optic neuropathy, whereby the prevalence increases sharply over the age of 60 and is associated with increased systemic tissue stiffness. On a molecular basis, this is associated with increased deposition of collagen and loss of elastin structure, resulting in aberrant biomechanical compliance and reduced tissue ...
Sarah, Powell, Mustapha, Irnaten, Colm, O'Brien   +2 more
openaire   +2 more sources

The Stiff Elbow [PDF]

Hand, 2009
Elbow motion is essential for upper extremity function to position the hand in space. Unfortunately, the elbow joint is prone to stiffness following a multitude of traumatic and atraumatic etiologies. Elbow stiffness can be diagnosed with a complete history and physical exam, supplemented with appropriate imaging studies. The stiff elbow is challenging
Peter J Evans
exaly   +3 more sources