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Stiff Person Syndrome and Pregnancy
Obstetrics & Gynecology, 2011Stiff person syndrome, also known as Moersche-Woltman syndrome, is a debilitating disorder that is rarely seen in the pregnant patient. It is characterized by muscle spasms triggered by startle, voluntary movement, or tactile or emotional stimuli, occurring predominantly in the axial musculature.A woman diagnosed with stiff person syndrome became ...
Jennifer, Goldkamp +2 more
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Diabetes in stiff-person syndrome
Trends in Endocrinology & Metabolism, 2023Anti-glutamic acid decarboxylase (GAD) autoantibodies are a hallmark of stiff-person syndrome (SPS) and insulin-dependent diabetes mellitus (IDDM). However, patients with concurrent IDDM and SPS often manifest insulin resistance, and SPS-associated IDDM probably has heterogeneous causes.
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The Neurologist, 2004
Stiff-person syndrome (SPS) is a rare neurologic disorder with autoimmune features. It is characterized by progressive, severe muscle rigidity or stiffness most prominently affecting the spine and lower extremities.Superimposed muscle spasms result in simultaneous contraction of agonist and antagonist muscles which are detectable by electromyography ...
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Stiff-person syndrome (SPS) is a rare neurologic disorder with autoimmune features. It is characterized by progressive, severe muscle rigidity or stiffness most prominently affecting the spine and lower extremities.Superimposed muscle spasms result in simultaneous contraction of agonist and antagonist muscles which are detectable by electromyography ...
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Levetiracetam in stiff-person syndrome
Journal of Neurology, 2008We studied the effects of oral levetiracetam (LEV) (500 mg twice daily) in three women with stiff-person syndrome in a single-blind, placebo-controlled study. The severity of muscle rigidity and of paroxysmal symptoms was assessed by EMG and clinically by a rating scale of 0-4 and by the Patients Global Impressions Scale. LEV was well tolerated.
Gianpietro, Sechi +5 more
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The Journal of the Association of Physicians of India, 2018
Stiff-person syndrome or Moersch-Woltmann is a very rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms involving axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system.
Han Na Kim, Nestoras Mathioudakis
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Stiff-person syndrome or Moersch-Woltmann is a very rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms involving axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system.
Han Na Kim, Nestoras Mathioudakis
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Neurology, 1998
The understanding of antibody-mediated neurologic diseases often emerges from a typical sequence of events. Initially, the symptoms and signs of the disorder are described along with the associated electrophysiologic findings, and clinical diagnostic criteria are established.
John T. Kissel, Rodger J. Elble
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The understanding of antibody-mediated neurologic diseases often emerges from a typical sequence of events. Initially, the symptoms and signs of the disorder are described along with the associated electrophysiologic findings, and clinical diagnostic criteria are established.
John T. Kissel, Rodger J. Elble
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Brain and nerve = Shinkei kenkyu no shinpo, 2021
Stiff-person syndrome (SPS) is a neurological disorder characterized by fluctuating muscle rigidity and painful spasms that occur spontaneously or are triggered by diverse stimuli. Partial or segmental forms of the disorder, such as stiff-limb syndrome (SLS) and the more severe disease called progressive encephalomyelitis with rigidity and myoclonus ...
Naoko, Matsui +2 more
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Stiff-person syndrome (SPS) is a neurological disorder characterized by fluctuating muscle rigidity and painful spasms that occur spontaneously or are triggered by diverse stimuli. Partial or segmental forms of the disorder, such as stiff-limb syndrome (SLS) and the more severe disease called progressive encephalomyelitis with rigidity and myoclonus ...
Naoko, Matsui +2 more
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The Journal of the Association of Physicians of India, 2001
This communication considers a patient with episodic muscle spasms. Pharmacological intervention and electrophysiological studies provided adequate evidence confirming the diagnosis of stiff person syndrome. Electrophysiological studies in present communication similar to earlier reports, confirmed once again the autonomous state of the anterior horn ...
J, Nikhilesh +3 more
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This communication considers a patient with episodic muscle spasms. Pharmacological intervention and electrophysiological studies provided adequate evidence confirming the diagnosis of stiff person syndrome. Electrophysiological studies in present communication similar to earlier reports, confirmed once again the autonomous state of the anterior horn ...
J, Nikhilesh +3 more
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2017
Stiff person syndrome is an uncommon neurological disease characterised by symmetrical muscle stiffness and spasms that often lead to skeletal deformity. Variants of this syndrome include the ‘stiff leg syndrome’ in which only one limb is involved and ‘progressive encephalomyelitis with rigidity and myoclonus’ in which we can find a variety of ...
Sonia Benítez-Rivero, Pablo Mir
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Stiff person syndrome is an uncommon neurological disease characterised by symmetrical muscle stiffness and spasms that often lead to skeletal deformity. Variants of this syndrome include the ‘stiff leg syndrome’ in which only one limb is involved and ‘progressive encephalomyelitis with rigidity and myoclonus’ in which we can find a variety of ...
Sonia Benítez-Rivero, Pablo Mir
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Defining the Expanding Clinical Spectrum of Pediatric-Onset Stiff Person Syndrome
Pediatric Neurology, 2021Anusha K Yeshokumar +2 more
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