Results 1 to 10 of about 30,715 (166)
Expanding the pH range of glutamate decarboxylase from L. pltarum LC84 by site-directed mutagenesis [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Glutamate decarboxylase is a class Ⅱ amino acid decarboxylase dependent onpyridoxal-5′-phosphate (PLP), which catalyzes the decarboxylation of substrateL-glutamate (L-Glu) to synthesize γ-aminobutyric acid (GABA).
Lijuan Yang +6 more
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Parallel Strategy Increases the Thermostability and Activity of Glutamate Decarboxylase [PDF]
Molecules, 2020 Glutamate decarboxylase (GAD; EC 4.1.1.15) is a unique pyridoxal 5-phosphate (PLP)-dependent enzyme that specifically catalyzes the decarboxylation of L-glutamic acid to produce γ-aminobutyric acid (GABA), which exhibits several well-known ...
Qing-Fei Zhang +5 more
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An examination of aspartate decarboxylase and glutamate decarboxylase activity in mosquitoes [PDF]
Molecular Biology Reports, 2009 A major pathway of beta-alanine synthesis in insects is through the alpha-decarboxylation of aspartate, but the enzyme involved in the decarboxylation of aspartate has not been clearly defined in mosquitoes and characterized in any insect species. In this study, we expressed two putative mosquito glutamate decarboxylase-like enzymes of mosquitoes and ...
Haizhen Ding +2 more
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Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice [PDF]
Molecular Brain, 2021 Reduced expression of glutamate decarboxylase 67 (GAD67), encoded by the Gad1 gene, is a consistent finding in postmortem brains of patients with several psychiatric disorders, including schizophrenia, bipolar disorder and major depressive disorder.
Shigeo Miyata +12 more
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Oxygen, 2023 Flooding induces low-oxygen stress, which reduces plant growth. The activity of the γ-aminobutyric acid (GABA) shunt is crucial for plant stress adaptation, in which it acts by changing cytosolic pH, limiting reactive oxygen species production ...
Setsuko Komatsu +2 more
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Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid tolerance. [PDF]
PLoS ONE, 2014 The glutamate decarboxylase (GAD) system has been shown to be important for the survival of Listeria monocytogenes in low pH environments. The bacterium can use this faculty to maintain pH homeostasis under acidic conditions.
Conor Feehily +6 more
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Glutamic Acid Decarboxylase in Legumes [PDF]
Nature, 1956 Since the pioneer researches of Okuniki1,2 and Schales and his associates3–5 on glutamic acid decarboxylase, rather scanty data have been made available on amino-acid decarboxylases of plants. Most of the work deals with glutamic acid decarboxylase of higher plants; so it was thought of interest to study the enzyme system in the case of dry seeds of ...
L, KULKARNI, K, SOHONIE
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Frontiers in Behavioral Neuroscience, 2015 Autoantibodies to the smaller isoform of glutamate decarboxylase can be found in patients with type 1 diabetes and a number of neurological disorders, including stiff-person syndrome, cerebellar ataxia and limbic encephalitis.
Mario U Manto +10 more
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SdiA Improves the Acid Tolerance of E. coli by Regulating GadW and GadY Expression
Frontiers in Microbiology, 2020 The acid tolerance mechanism is important for Escherichia coli to resist acidic conditions encountered in mammalian host digestive tract environment. Here, we explored how the LuxR protein SdiA influenced E.
Xingyan Ma +16 more
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Noise and Health, 2014 Chronic stress induces neurochemical changes that include neurotransmitter imbalance in the brain. Noise is an environmental factor inducing stress. Chronic noise stress affects monoamine neurotransmitter systems in the central nervous system. The effect
Amajad Iqbal Kazi, Anna Oommen
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