Results 131 to 140 of about 25,417,473 (341)

Determining Initial Values for Stiff Systems with Incomplete Initial Data

open access: yes, 1980
Stiff differential equations frequently arise in physical problems due to the existence of greatly differing time constants. One way of solving stiff differential equations is taking the step size very small, another way is using an A-stable or stiffly ...
Ning, Yech-Kuang
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Stiff systems

open access: yesScholarpedia, 2007
Lawrence F. Shampine, Skip Thompson
openaire   +1 more source

Efficient detection of periodic orbits in high dimensional systems

open access: yes, 2005
This paper is concerned with developing a method for detecting unstable periodic orbits (UPOs) by stabilising transformations. Here the strategy is to transform the system of interest in such away that the orbits become stable.
Crofts, JJ, Davidchak, RL
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Investigating the Surrogate Modeling Capabilities of Continuous Time Echo State Networks

open access: yesMathematical and Computational Applications
Continuous Time Echo State Networks (CTESNs) are a promising yet under-explored surrogate modeling technique for dynamical systems, particularly those governed by stiff Ordinary Differential Equations (ODEs).
Saakaar Bhatnagar
doaj   +1 more source

Third Derivative Multistep Methods for Stiff Systems

open access: yes, 2012
: In this paper, we present a class of multistep methods for the numerical solution of stiff ordinary differential equations. In these methods the first, second and third derivatives of the solution are used to improve the accuracy and absolute stability
Ali K Ezzeddine, Gholamreza Hojjati
core  

Integral tau methods for stiff stochastic chemical systems

open access: yes, 2011
Tau leaping methods enable efficient simulation of discrete stochastic chemical systems. Stiff stochastic systems are particularly challenging since implicit methods, which are good for stiffness, result in noninteger states.
Rathinam, Muruhan   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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