Results 151 to 160 of about 9,010,138 (290)

Soft microgel networks stabilize and extend nozzle-free water jets. [PDF]

Nat Commun
Razavi A, Roudini M, Winkler A, Liebchen B, von Klitzing R, Mandal S, Rahimzadeh A.   +6 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Extracellular matrix composition and stiffness regulates progesterone responsiveness and decidualization. [PDF]

iScience
Klunk D, Homewood L, Abebayehu D.
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique. [PDF]

CVIR Endovasc
Corti R, Ambrosi L, Cionfoli N, D'Agostino MA, Quaretti P, Bozzani A.   +5 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Spontaneous Curvature Sculpts Filament-Vesicle Morphogenesis. [PDF]

Nano Lett
Fang Y, Zhang C, Wang M, Shi C, Yi X.
europepmc   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Mechanosensitive phosphorylation of NFATC4 at S213/S217 drives fibroblast-to-myofibroblast transition and fibrosis. [PDF]

J Clin Invest
Kadri S, Mattner LF, Zeng Z, Prakki SRS, Verma AK, Cetin U, Mayr CH, Ansari M, Wei X, Asgharpour S, Wasik AA, Kneidinger N, Stoleriu MG, Behr J, Polleux J, Yildirim AÖ, De Sadeleer LJ, Wuyts WA, Burgstaller G, Mann M, Mück-Häusl M, Schiller HB.   +21 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source