Results 51 to 60 of about 283,093 (291)
Optimal prediction of stiff oscillatory systems [PDF]
We consider some large systems of differential equations that have been introduced as model many-body problems. These systems have solutions that oscillate on a wide range of time scales. We apply the formalism of optimal prediction to these systems, using conditional expectations of the equations of motion to construct effective equations for the most
openaire +5 more sources
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Sparsing in Real Time Simulation [PDF]
Modelling of mechatronical systems often leads to large DAEs with stiff components. In real time simulation neither implicit nor explicit methods can cope with such systems in an efficient way: explicit methods have to employ too small steps and implicit
Bornemann, Folkmar, Schiela, Anton
core +1 more source
The article provides an overview of cases of stiffness, leading to inadequate results of mathematical models of mechanics. An attempt is made to generalize look at this phenomenon for body dynamics, and for the continuum mechanics.
M. S. Kublanov
doaj
In this paper, we establish that for a wide class of controlled stochastic differential equations (SDEs) with stiff coefficients, the value functions of corresponding zero-sum games can be represented by a deep artificial neural network (DNN), whose ...
Reisinger, Christoph, Zhang, Yufei
core +1 more source
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Construction of efficient general linear methods for non-stiff differential systems
This paper describes the construction of explicit general linear methods in Nordsieck form with inherent quadratic stability and large areas of the stability region.
Michal Bra´s, Angelamaria Cardone
doaj +1 more source
The parallel connection of technical and biological systems with a comparable mechanical behavior offers the possibility of reducing the interaction forces between those systems.
Max Jäger +4 more
doaj +1 more source
Fluctuation spectra of free and supported membrane pairs
Fluctuation spectra of fluid compound membrane systems are calculated. The systems addressed contain two (or more) almost parallel membranes that are connected by harmonic tethers or by a continuous, harmonic confining potential.
Merath, Rolf-Juergen, Seifert, Udo
core +1 more source
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source

