Results 81 to 90 of about 9,010,138 (290)

Krylov Implicit Integration Factor Methods for Semilinear Fourth-Order Equations

Mathematics, 2017
Implicit integration factor (IIF) methods were developed for solving time-dependent stiff partial differential equations (PDEs) in literature. In [Jiang and Zhang, Journal of Computational Physics, 253 (2013) 368–388], IIF methods are designed to ...
Michael Machen, Yong-Tao Zhang
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Load compensation for systems with non-stiff source using state feedback

, 2003
Various load compensation schemes proposed in literature assume that voltage source at point of common coupling (PCC) is stiff. In practice, however, the load is remote from a distribution substation and is supplied by a feeder. In the presence of feeder
Ghosh, Arindam, Mishra, Mahesh, Joshi, Avinash   +2 more
core   +1 more source

An efficient numerical algorithm for the transient analysis of high-frequency non-linear circuits [PDF]

, 2002
The paper proposes a new approach for the discrete-time integration of non-linear differential equations that describe the behaviour of high-frequency circuits, in particular those containing complex equivalent-circuit models of microwave transistor ...
Condon, Marissa, Brazil, T. J., M. Condon, E. Dautbegovic, T. J. Brazil, Dautbegovic, Emira   +5 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A ninth-order first derivative method for numerical integration

Journal of Nigerian Society of Physical Sciences
In this paper, we present a ninth–order block hybrid method for the numerical solution of stiff and non–stiff systems of first–order differential equations.
Richard Akinola, Ezekiel Omole, Joshua Sunday, Stephen Kutchin   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Evaluation of capacities of bucket foundations in soft-stiff-soft clays under combined loading

, 2021
Bucket foundations are widely constructed for offshore wind turbines, which are subjected to combined vertical-horizontal-moment (V-H-M) loading during operation.
Xihong Zhang (23289454), Ningxin Yang (1521529), YInghui Tian (23521204), Mi Zhou (9884)   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source