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Nanocrystals as Tool to Enhance Stigmasterol Oral Bioavailability
Journal of Nanoscience and Nanotechnology, 2021 Phytosterols are sterols naturally occurring in plant cells and well known for their cholesterollowering activity, as witnessed by the large number of food supplements based on these functional ingredients available on the market. However, the marked hydrophobic character of phytosterols makes their solubility in biological fluids extremely low, with ...
Pireddu, Rosa +7 more
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Biosynthesis of Stigmasterol in Tomato Fruits
Science, 1961 The presence of stigmasterol in tomato fruits was demonstrated. Labeled mevalonic acid was incorporated into this sterol, while sodium acetate was not. The identity of the isolated product was established by rigorous purification to constant specific activity, melting point determinations, and infrared ...
Bennett, Raymond D. +3 more
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Stigmasterol: An Enigmatic Plant Stress Sterol with Versatile Functions
International Journal of Molecular SciencesSterols play important structural and regulatory roles in numerous intracellular processes. Unlike animals, plants contain a distinctive and diverse variety of sterols. Recently, information has emerged showing that stigmasterol is a “stress sterol&
Richard P Beckett, Farida V Minibayeva
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Acta Crystallographica Section C Crystal Structure Communications, 2002
The title compound, stigmasta-5,22-dien-3beta-ol hemihydrate, C(29)H(48)O x 0.5H(2)O, previously thought to be the monohydrate, has two sterol molecules and one water molecule in the asymmetric unit. In both sterol molecules, the methyl group of the ethyl substituent at the end of the hydrocarbon chain is disordered over two sites.
Gloria A, Benavides +2 more
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The title compound, stigmasta-5,22-dien-3beta-ol hemihydrate, C(29)H(48)O x 0.5H(2)O, previously thought to be the monohydrate, has two sterol molecules and one water molecule in the asymmetric unit. In both sterol molecules, the methyl group of the ethyl substituent at the end of the hydrocarbon chain is disordered over two sites.
Gloria A, Benavides +2 more
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Absolute configuration assignment of stigmasterol oxiranes
Chirality, 2021AbstractDiastereoisomeric stigmasterol oxiranes 4, 5, 8, and 9 are known phytosterol oxidation products (POPs) that have been evaluated for their cytotoxicity, although the results are of limited significance since, in most cases, they were evaluated as mixtures.
Miguel Á. Fuentes‐Figueroa +2 more
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Polyamine conjugates of stigmasterol
Steroids, 2012Three new polyamine conjugates with stigmasterol [(3β,22E)-stigmasta-5,22-dien-3-ol] were synthesized and subjected to basic antimicrobial and cytotoxic tests. The conjugate derived from spermine, (3β,22E)-stigmasta-5,22-dien-3-yl 4(12-amino-4,9-diaza-dodecylamino)-4-oxobutanoate (5c), displayed considerable antimicrobial activity on Staphylococcus ...
Vida, Norbert +6 more
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Lipids, 1973
AbstractHydrogenations of stigmasterol over 5% Pd/C, 5% Ru/C, Pt, Raney Ni, Raney Co, Ni/kieselguhr, and tris(triphenylphosphine)chlororhodium catalysts and with diimide generated from hydrazine andp‐toluenesulfonylhydrazide were studied to determine the best conditons for the selective reduction of the Δ22 double bond.
Henry W. Kircher, Fumiko U. Rosenstein
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AbstractHydrogenations of stigmasterol over 5% Pd/C, 5% Ru/C, Pt, Raney Ni, Raney Co, Ni/kieselguhr, and tris(triphenylphosphine)chlororhodium catalysts and with diimide generated from hydrazine andp‐toluenesulfonylhydrazide were studied to determine the best conditons for the selective reduction of the Δ22 double bond.
Henry W. Kircher, Fumiko U. Rosenstein
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Stigmasterol Tetracosanoate, a New Stigmasterol Ester from the Egyptian Blepharis ciliaris
Drug Research, 2014A new stigmasterol ester: stigmasterol tetracosanoate (3), along with 7 compounds: β-sitosterol (1), stigmasterol (2), (2S,3S,4R)-2[(2'R)-2'-(hydroxyeicosanoyl amino) octadecane-1,3,4-triol (4), apigenin (5), β-sitosterol-3-O-β-D-glucopyranoside (6), stigmasterol-3-O-β-D-glucopyranose (7), and apigenin-7-O-β-D-glucopyranoside (8) were isolated from ...
M A, El-Shanawany +3 more
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Stigmasterol Removal by an Aerobic Treatment System
2023Stigmasterol is a phytosterol contained in kraft mill effluent that is able to increase over 100% after aerobic biological treatment. This compound can act as an endocrine disrupter as its structure is similar to that of cholesterol. Furthermore, stigmasterol contained in kraft mill effluent shows high toxicity (25-fold more than β-sitosterol) to ...
Soledad, Chamorro +2 more
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