Results 181 to 190 of about 10,463 (208)

Synthesis and Characterization of Stigmasterol Oxidation Products

Journal of Agricultural and Food Chemistry, 2010
The synthesis and structural characterization of a series of oxides of stigmasterol is described providing a valuable series of reference standards for these oxides, analogous to the cholesterol oxidation products (COPs) which have been shown to have detrimental biological effects.
David A, Foley, Yvonne, O'Callaghan, Nora M, O'Brien, Florence O, McCarthy, Anita R, Maguire   +4 more
openaire   +2 more sources

Nanocrystals as Tool to Enhance Stigmasterol Oral Bioavailability

Journal of Nanoscience and Nanotechnology, 2021
Phytosterols are sterols naturally occurring in plant cells and well known for their cholesterollowering activity, as witnessed by the large number of food supplements based on these functional ingredients available on the market. However, the marked hydrophobic character of phytosterols makes their solubility in biological fluids extremely low, with ...
Pireddu, Rosa, Sinico, Chiara, Ennas, Guido, Valenti, Donatella, Marongiu, Francesca, Maria Fadda, Anna, Schlich, Michele, Lai, Francesco   +7 more
openaire   +3 more sources

Short-step Synthesis of Chenodiol from Stigmasterol

Bioscience, Biotechnology, and Biochemistry, 2004
Chenodiol is an important bile acid widely used for gallstone dissolution and cholestatic liver diseases. We succeeded in a short-step synthesis of chenodiol, starting from the safer phytosterol, stigmasterol.
Toru, Uekawa, Ken, Ishigami, Takeshi, Kitahara   +2 more
openaire   +2 more sources

Stigmasterol Removal by an Aerobic Treatment System

2017
Stigmasterol is a phytosterol contained in Kraft mill effluent that is able to increase over 100% after aerobic biological treatment. This compound can act as an endocrine disrupter as its structure is similar to that of cholesterol. Furthermore, stigmasterol contained in Kraft mill effluent shows high toxicity (25-fold that of β-sitosterol) to aquatic
Soledad, Chamorro, Claudia, Xavier, Víctor, Hernández, José, Becerra, Gladys, Vidal   +4 more
openaire   +2 more sources

Oxidation of stigmasterol in heated triacylglycerols

Food Chemistry, 1989
Abstract A triacylglycerol mixture containing 5% stigmasterol by weight and devoid of other unsaponifiables was heated at 180 ± 5°C for several hours. Oxidation products from stigmasterol were separated and isolated by column chromatography and preparative thin-layer chromatography.
George Blekas, Dimitrios Boskou
openaire   +1 more source

Semi‐synthesis of Several Stigmasterol Saponins

Chinese Journal of Chemistry, 2006
AbstractSeveral stigamasterol saponins were concisely synthesized. Namely, four monosaccharide (glucopyranose, galactopyranose, xylopyranose, 2‐acetamido‐2‐deoxy‐α‐D‐glucopyranose), lactopyranose and chacotriose were coupled with 3‐OH of stigmasterol. All the compounds were identified by NMR, IR and high resolusion MS.
Chun‐Xia Li, Tian‐Tian Guo, Peng Wang, Hua‐Shi Guan, Ying‐Xia Li   +4 more
openaire   +1 more source

Synthesis of 22,23-Epoxyecdysteroids from Stigmasterol

Chemistry of Natural Compounds, 2001
A new synthetic scheme has been developed to synthesize 22,23-epoxyecdysteroids from ...
N. V. Kovganko, V. L. Survilo
openaire   +1 more source

Biosynthesis of stigmasterol from sitosterol in Digitalis Lanata

Steroids, 1969
Abstract After administration of sitosterol-3-14C to a Digitalis lanata plant, radioactive stigmasterol was isolated by chromatography and shown to be radiochemically pure by crystallization to constant specific activity.
R D, Bennett, E, Heftmann
openaire   +2 more sources

Antihypercholesterolemic Studies with Sterols: β-Sitosterol and Stigmasterol

Journal of Pharmaceutical Sciences, 1979
Stigmasterol, which differs from beta-sitosterol by unsaturation at C22, was tested for antihypercholesterolemic activity under an experimental protocol that gave the results expected with beta-sitosterol and cholestyramine. In terms of serum cholesterol, stigmasterol had a barely significant antihypercholesterolemic effect while exhibiting no obvious ...
R F, Chandler, S N, Hooper, H A, Ismail
openaire   +2 more sources

New Synthesis of 28‐Homobrassinolide from Stigmasterol

Liebigs Annalen, 1997
AbstractAn efficient and short synthesis of 28‐homobrassinolide (6) has been achieved in 12 steps with 15.6% overall yield from stigmasterol (8). Salient features of this synthesis are: (a) use of tetradecyltrimethylammonium permanganate for chemoselective cis‐dihydroxylation of the 2,22E‐dien‐6‐one 9, avoiding the use of OsO4; (b) one‐step epoxidation
Braja G. Hazra, Tirunahari Pavan Kumar, Padmakar L. Joshi   +2 more
openaire   +1 more source