Results 141 to 150 of about 4,864,129 (252)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Steroid-Refractory Adult-Onset Still's Disease: A Case Report. [PDF]

Cureus
Kyaw PP, Mon T, Thu PP, Nyein A.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Adult-onset Still's disease: Sequential atypical rashes-Persistent plaques and flagellate erythema. [PDF]

JAAD Case Rep
Downey K, Haroon A, Seervai RNH, Mengden SJ, Faridi CH, Bressler MY, Fett NM, Keller JJ.   +7 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Adult-Onset Still's Disease as an Uncommon Cause of Fever of Unknown Origin. [PDF]

Cureus
Andujar Sanchez YA, Moran L, Belmontes Gutiérrez DA, Moreno Velazco PA, Isais Moreno DM.   +4 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Unfolding dermatological spectrum of Still's disease: a cohort study from the International AIDA Network Still's Disease Registry. [PDF]

Rheumatology (Oxford)
Calabrese L, D'Onghia M, Cartocci A, Hinojosa-Azaola A, Torres-Ruiz J, Lopalco G, Sbalchiero J, Caggiano V, Giardini HAM, Almaghlouth IA, Ruscitti P, Di Cola I, Sfikakis PP, Laskari K, Sfriso P, Dagna L, Campochiaro C, Tufan A, Kucuk H, Kardas RC, Erden A, Ragab G, Hegazy MT, Laymouna AH, Navarini L, Berardicurti O, Ciccia F, Iacono D, Riccio F, Fotis L, Direskeneli H, Makowska J, Iagnocco A, Conforti A, Rigante D, Thabet M, Iannone F, Domanico D, Govoni M, Maggio MC, Del Giudice E, La Torre F, Batu ED, Ozen S, Gaggiano C, Martín-Nares E, Guaracha-Basañez GA, Karamanakos A, Lo Gullo A, Monosi B, Bartoloni E, Hernández-Rodríguez J, Gómez-Caverzaschi V, Emmi G, Erten S, Carubbi F, Gicchino MF, De Paulis A, Conti G, Ogunjimi B, Wiesik-Szewczyk E, Nowakowska-Płaza A, Viapiana O, Sarzi-Puttini P, Tharwat S, Crisafulli F, Parronchi P, Gidaro A, De Stefano L, Breda L, La Barbera L, Guggino G, Balistreri A, Fabiani C, Rubegni P, Frediani B, Giacomelli R, Cantarini L, Vitale A, International AIDA (AutoInflammatory Diseases Alliance) Network and the Autoinflammatory Diseases Working Group of the Italian Society of Rheumatology (SIR).   +79 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source