Results 201 to 210 of about 40,978 (244)

Redox modulation of STIM-ORAI signaling [PDF]

open access: yesCell Calcium, 2016
STIM1 and ORAI1 constitute the core machinery of the ubiquitous store-operated calcium entry pathway and loss of function in these proteins is associated with severe immune and muscular disorders.
Rajesh Bhardwaj   +2 more
exaly   +3 more sources
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STIM

Proceedings of the 14th International Conference on Information Processing in Sensor Networks, 2015
Globally, infrastructure is a vital asset for economic prosperity, but condition assessments tend to be subjective and infrequent [2]. The lack of objective information leads to sub-optimal capital replacement projects, and the information lag prevents timely repair. In this poster we focus on techniques for monitoring rail-based transit infrastructure,
George Lederman   +2 more
openaire   +1 more source

Limited angle STIM and PIXE tomography of single cells [PDF]

open access: yesNuclear Instruments & Methods in Physics Research B, 2010
STIM (scanning transmission ion microscopy) tomography has been shown to be a valuable method for the three-dimensional characterization of microsamples. It has, however, rarely been employed for the study of single cells, since a free-standing sample is
T Reinert
exaly   +2 more sources

The STIM-Orai Pathway: The Interactions Between STIM and Orai

2017
A primary Ca2+ entry pathway in non-excitable cells is established by the Ca2+ release-activated Ca2+ channels. Their two limiting molecular components include the Ca2+-sensor protein STIM1 located in the endoplasmic reticulum and the Orai channel in the plasma membrane.
Marc, Fahrner   +4 more
openaire   +2 more sources

Molecular mechanisms of STIM/Orai communication [PDF]

open access: yesAmerican Journal of Physiology - Cell Physiology, 2016
Ca2+ entry into the cell via store-operated Ca2+ release-activated Ca2+ (CRAC) channels triggers diverse signaling cascades that affect cellular processes like cell growth, gene regulation, secretion, and cell death. These store-operated Ca2+ channels open after depletion of intracellular Ca2+ stores, and their main features are fully reconstituted by
Isabella Derler   +2 more
exaly   +3 more sources

Development of STIM

SPIE Proceedings, 2003
n order to studying long-term climate variability and globe environment change, Solar Total Irradiance Monitor (STIM) is constructed planed to aboard on FY-3 sun-synchronous polar orbit weather satellites. STIM is made up of three same absolute radiometers, which are similar with Solar Irradiance Absolute Radiometers (SIAR). We designate one radiometer
Wei Fang   +5 more
openaire   +1 more source

The STIM-Orai Pathway: STIM-Orai Structures: Isolated and in Complex

2017
Considerable progress has been made elucidating the molecular mechanisms of calcium (Ca2+) sensing by stromal interaction molecules (STIMs) and the basis for Orai channel activity. This chapter focuses on the available high-resolution structural details of STIM and Orai proteins with respect to the regulation of store-operated Ca2+ entry (SOCE ...
Jinhui, Zhu   +2 more
openaire   +2 more sources

Scanning transmission ion microscopy computed tomography (STIM-CT) for inertial confinement fusion (ICF) targets [PDF]

open access: yesFusion Engineering and Design, 2013
ICF target quality control in the laser fusion program is vital to ensure that the energy deposition from the lasers results in uniform compression and minimization of Rayleigh-Taylor instabilities, which requires surface finishes on the order of ...
Y Q Li
exaly   +2 more sources

STIM and Orai in platelet function

Cell Calcium, 2011
Physiological platelet activation and thrombus formation are essential to stop bleeding in case of vascular injury, whereas inadequate triggering of the same process in diseased vessels can lead to fatal thromboembolism and tissue ischemia of vital organs.
David, Varga-Szabo   +2 more
openaire   +2 more sources

The STIM-Orai Pathway: Regulation of STIM and Orai by Thiol Modifications

2017
Cysteines are among the least abundant amino acids found in proteins. Due to their unique nucleophilic thiol group, they are able to undergo a broad range of chemical modifications besides their known role in disulfide formation, such as S-sulfenylation (-SOH), S-sulfinylation (-SO(2)H), S-sufonylation (-SO(3)H), S-glutathionylation (-SSG), and S ...
openaire   +2 more sources

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