Results 201 to 210 of about 43,138 (232)
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To Stim and Then Map, or Map and Then Stim, That is the Question

Circulation: Arrhythmia and Electrophysiology, 2023
Timothy M. Markman, David S. Frankel
openaire   +2 more sources

STIM-TRP Pathways

2011
Store-operated Ca2+ entry (SOCE) is activated in response to depletion of the ER-Ca2+ stores. Upon Ca2+ store depletion, the ER Ca2+ sensor protein, STIM1, oligomerizes and moves to ER/PM junctional domains where it interacts with and activates channels involved in SOCE; namely Orai and TRPC channels.
Indu S. Ambudkar   +3 more
openaire   +2 more sources

High resolution STIM

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1989
Abstract Scanning transmission ion microscopy (STIM) is a technique whereby the imaging resolution of a scanning proton microprobe (SPMP) can be improved by one or two orders of magnitude. This has major applications in medicine and biology where it may be needed for identification, resolution of fine structure or imaging a specimen of intrinsically ...
G.S. Bench, G.J.F. Legge
openaire   +1 more source

STIM-TRP Pathways and Microdomain Organization: Auxiliary Proteins of the STIM/Orai Complex

2017
The basic paradigm of a mechanism for calcium influx triggered after a reduction on calcium store content implies a sensor of calcium concentration on the endoplasmic reticulum (the stores) and a calcium channel immersed on the plasma membrane. These two basic components are STIM and Orai, the most fundamental and minimal molecular constituents of the ...
Jonathan, Pacheco, Luis, Vaca
openaire   +2 more sources

A STIM for Resting Cells

Science Signaling, 2008
One of the "Breakthroughs of the Year" noted in last year’s compendium at STKE was the discovery of the role of STIM proteins, particularly STIM1, in coupling stimulus-induced depletion of intracellular calcium stores to influx of extracellular calcium through the plasma membrane calcium channel Orai1. Brandman et al
openaire   +1 more source

STIM Proteins and Regulation of SOCE in ER-PM Junctions

Biomolecules, 2022
Indu Ambudkar   +2 more
exaly  

The STIM-Orai Pathway

2011
Peter B. Stathopulos, Mitsuhiko Ikura
  +4 more sources

STIM and Orai Mediated Regulation of Calcium Signaling in Age-Related Diseases

Frontiers in Aging, 2022
John Chatham, Helen E Collins
exaly  

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