Results 51 to 60 of about 15,421,997 (282)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Advances and Considerations in Attention-Deficit/Hyperactivity Disorder Pharmacotherapy [PDF]
Acta Medica Iranica, 2011 Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric disorder associated with significant impairments in occu¬pational, academic, neuropsychological, and social functioning.
Shahin Akhondzadeh, Mohammad Mohammadi
doaj +2 more sources
231 The CoMBo Study: Combined Contingency Management for Both Stimulant Use and HIV
Journal of Clinical and Translational ScienceOBJECTIVES/GOALS: Contingency management (CM), wherein patients earn prizes for behavior change, is the gold-standard for reducing stimulant misuseand has been shown to improve medication adherence.We aim to describe the feasibility, acceptability, and ...
Gabriela Steiner +7 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
ADHD IN ADULTS: COMORBODITY WITH BIPOLAR DISORDER AND SUBSTANCE ABUSE [PDF]
, 2011 ADHD is characterized by a continuous history of hyperactivity, forgetfulness, distractibility, impulsiveness and/or inattention, starting from the early childhood and at a more severe extent than whatever may be usual in peers.
CERAUDO, GIUSEPPE
core
Identification of distinct stimulant use trajectories and patterns of overdose
Addictive Behaviors ReportsOverdoses in the United States are increasingly driven by co-occurring stimulant and fentanyl use, yet limited research has examined individual-level stimulant use patterns over time. We assessed self-reported stimulant use among 505 people who use drugs
Leah C. Shaw +8 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Stimulant safe supply: a potential opportunity to respond to the overdose epidemic
Harm Reduction Journal, 2020 Background Occurring against the backdrop of an overdose crisis, stimulant use and stimulant-involved deaths in North America are increasing at an alarming rate.
Taylor Fleming +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Morphometric similarity deviations in stimulant use disorder point towards abnormal brain ageing. [PDF]
, 2022 Chronic drug use negatively impacts ageing, resulting in diminished health and quality of life. However, little is known about biomarkers of abnormal ageing in stimulant drug users.
Dalley, Jeffrey W. +5 more
core +3 more sources