Results 81 to 90 of about 15,421,997 (282)

What influences clinicians’ decisions about ADHD medication? Initial data from the "influences on prescribing for ADHD questionnaire" (IPAQ) [PDF]

, 2013
Despite evidence for its efficacy and effectiveness, the use of medication for the treatment of ADHD remains controversial. Little is known about the factors that influence clinicians’ decisions to use medication for ADHD.
Thompson, Margaret, Yardley, Lucy, Hodgkins, Paul, Barke, Edmund, Vrijens, May, Danckaerts, Marina, Sonuga-Barke, E, Kovshoff, Hanna   +7 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Dual diagnosis: how adults diagnosed with bipolar disorder experience in-patient substance abuse treatment for stimulant use disorder

Social Work/Maatskaplike Werk, 2019
Dual diagnosis has become a topic of interest in recent years. In South Africa individuals diagnosed with dual diagnosis are left without adequate services as a result of the separation of substance abuse and mental health treatment services.
Van Zyl, Karina , Geyer, Stephan
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Evaluation and Management of Stimulant Use Disorder in Primary Care

Outline Case Background Legal history Scope of the Issue Screening Taking a History Diagnosis Treatment Harm Reduction Will not cover in depth: management of acute stimulant intoxication, management of complications from stimulant use, stimulant ...
Mandel, MD, Maia
core   +1 more source

Suicide and psychiatric disorders associated with amphetamine type stimulant use: a systematic review and meta-analysis

Frontiers in Psychiatry
ObjectiveThis study reviews the literature to determine the prevalence and nature of suicidality and psychiatric comorbidity in individuals with amphetamine-type stimulant (ATS) use to inform targeted interventions.MethodsWe searched the Web of Science ...
Halima Mohammed Adam, Ahmed Hamed Aljadani, Mohamed Abouzed, Benayan Bani Alrasheedy, Muath Abdulaziz Alarfaj   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Correlates of fentanyl preference among people who use drugs in Rhode Island

Harm Reduction Journal
Background Fentanyl is increasingly pervasive in the unregulated drug supply and is a driver of drug overdose deaths in the United States. The aims of this study were to characterize and identify correlates of fentanyl preference among people who use ...
Siena C. Napoleon, Carolyn J. Park, Jacqueline Goldman, Yu Li, Jane A. Buxton, Alexandria Macmadu, Katie B. Biello, Julia Noguchi, Brandon D.L. Marshall   +8 more
doaj   +1 more source