Results 51 to 60 of about 1,526,379 (284)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Improved Crystalline Quality of AlN by Epitaxial Lateral Overgrowth Using Two-Phase Growth Method for Deep-Ultraviolet Stimulated Emission

IEEE Photonics Journal, 2016
We report on the maskless epitaxial lateral overgrowth (ELOG) of the AlN layer on trench-patterned AlN/sapphire templates by metal-organic chemical vapor deposition (MOCVD).
Xiang Chen, Jianchang Yan, Yun Zhang, Yingdong Tian, Yanan Guo, Shuo Zhang, Tongbo Wei, Junxi Wang, Jinmin Li   +8 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The problem of dating quartz 1 : Spectroscopic ionoluminescence of dose dependence [PDF]

, 2010
This work is partially supported by NERC studentship F008589/1.A suite of quartz samples of different provenances, irradiation, thermal and depositional histories were analysed using spectroscopic ionoluminescence (IL) to investigate variations in ...
Robinson, Ruth Alison Joyce, Hole, D E, G.E. King, R.A.J. Robinson, King, Georgina, Finch, Adrian Anthony, D.E. Hole, A.A. Finch   +7 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Stimulated Emission from InAs (GaAs) Monolayers Stacks Embedded in Al0.33Ga0.67As Ective Region

Advances in Electrical and Electronic Engineering, 2002
Our study is focused on the optical and electronic properties of InAs (GaAs) monolayers embedded in Al0.33GA0.67As barrier layers investigated by temperature dependencies of electroluminescence spectra.
Dusan Pudis, Jaroslav Kovac, Jaroslav Kovac, Jan Jakabovic, Andrej Vincze, Sieler Gottschalch, Gabriele Benndorf, Bernd Rheinländer, Reinhard Schwabe   +8 more
doaj  

Polarized Stimulated Emission of 2D Ensembles of Plasmonic Nanolasers

Advanced Photonics Research, 2021
Plasmonic nanolasers produce coherent light with wavelengths on a scale similar to their own or larger. In the past decade they have attracted intense interest, particularly from the emerging areas of integrated photonic circuits and biomedicine. Despite
Nikita Toropov, Aisylu Kamalieva, Anton Starovoytov, Sajid Zaki, Tigran Vartanyan   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Ultraviolet Stimulated Emission from Sol-Gel Spin Coated ZnO Thin Films

Advances in Materials Science and Engineering, 2017
Low cost ultraviolet stimulated emission has been generated using optical excitation of ZnO thin films deposited by sol-gel spin coating on n+ As-doped 100 Si-substrate.
Ahmed S. Razeen, A.-S. Gadallah, M. M. El-Nahass   +2 more
doaj   +1 more source