Results 111 to 120 of about 5,580,781 (423)

CARDIAC STIMULANTS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1903
n ...
openaire   +2 more sources

The Dynamic Shift of Neuron Excitability Observed with Enveloped High Frequency Stimulation [PDF]

open access: yesarXiv, 2018
Neuronal excitability is known to be affected by transcranial electrical stimulation. However, due to the existence of both excitatory and inhibitory neurons in the cortex, the mechanism of neuronal excitability shift is still not clear. Here, we study electrical stimulation disturbance on neuronal excitability in the neuromuscular system on an acute ...
arxiv  

Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering

open access: yesBiomaterials Research, 2019
Recently, electrical stimulation as a physical stimulus draws lots of attention. It shows great potential in disease treatment, wound healing, and mechanism study because of significant experimental performance.
Cen Chen   +3 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Inhibit My Disinhibition: The Role of the Inferior Frontal Cortex in Sexual Inhibition and the Modulatory Influence of Sexual Excitation Proneness

open access: yesFrontiers in Human Neuroscience, 2018
Sexual behaviour is the result of an interplay between distinct neural inhibitory and excitatory mechanisms. Individual differences in sexual excitation and sexual inhibition are proposed to play an important role in the processes sustaining the ...
Geraldine Rodriguez   +3 more
doaj   +1 more source

Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

open access: yesBrain Stimulation, 2017
Transcranial electric stimulation aims to stimulate the brain by applying weak electrical currents at the scalp. However, the magnitude and spatial distribution of electric fields in the human brain are unknown.

semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

LTP-like cortical plasticity predicts conversion to dementia in patients with memory impairment

open access: yesBrain Stimulation, 2020
Background: New diagnostic criteria consider Alzheimer’s disease (AD) as a clinico-biological entity identifiable in vivo on the presence of specific patterns of CSF biomarkers. Objective: Here we used transcranial magnetic stimulation to investigate the
Francesco Di Lorenzo   +7 more
doaj  

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