Results 131 to 140 of about 4,214,353 (299)

Deep brain stimulation: current challenges and future directions

open access: yesNature Reviews Neurology, 2019
A. Lozano   +12 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)

open access: yesClinical Neurophysiology, 2017
J. Lefaucheur   +22 more
semanticscholar   +1 more source

Dengue Virus Directly Stimulates Polyclonal B Cell Activation

open access: gold, 2015
Arturo Vargas Correa   +5 more
openalex   +2 more sources

Novel bifunctional cap for simultaneous electroencephalography and transcranial electrical stimulation [PDF]

open access: gold, 2018
Sophia Wunder   +5 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The role of electron-stimulated desorption in focused electron beam induced deposition [PDF]

open access: diamond, 2013
Willem F. van Dorp   +3 more
openalex   +1 more source

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