Results 91 to 100 of about 233,089 (385)
Epigenetic state determines the in vivo efficacy of STING agonist therapy
Nature Communications, 2023 STING agonists have shown limited efficacy in early-phase clinical trials despite promising pre-clinical data. This study shows the potential clinical relevance of the use of combination STING agonists and demethylating agent therapies to induce the ...
Rana Falahat +8 more
semanticscholar +1 more source
A Different Perspective on the Solid Lubrication Performance of Black Phosphorous: Friend or Foe?
Advanced Engineering Materials, EarlyView.Researchers investigate black phosphorous (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli +5 more
wiley +1 more source
Effects of the STING R232/H232 Variant on the Prognosis of Inflammatory Bowel Disease
Journal of Pediatric ResearchAim: Inflammatory bowel disease (IBD) refers to a group of diseases which cause chronic and recurrent inflammation in different parts of the digestive tract, such as Crohn’s disease (CD) or ulcerative colitis (UC).
Gizem Akyol +4 more
doaj +1 more source
Method for static divergence analysis of sting-mounted wind tunnel models [PDF]
, 2005 Occurrence of static divergence will result in a catastrophic failure of wind tunnel models supported13; on sting or other types of support . The report presents an analysis method that can be used to design and/or13; verify the design of a model-balance-
Sundaramurthy, H
core
Top-down, bottom-up, or both? Toward an integrative perspective on operations strategy formation [PDF]
, 2014 Operations strategy is formed via complex processes that transpire in multiple directions at multiple organizational levels. While most previous studies focus on the “macro-level” process of strategy formation from the dominant top-down perspective, this
Kim, YH, Loch, CH, Sting, FJ
core +1 more source
Advanced Engineering Materials, EarlyView.Ultrahigh‐molecular‐weight polyethylene powders (<≈40 μm) with a bulk density of 260 g L−1 are prepared from a silica supported bisimine pyridine iron catalyst. The nascent product is disentangled and can be thermally densified without loss of its low viscosity.
Adrian Vaghar +4 more
wiley +1 more source
A quantitative method to monitor STING degradation with dual-luciferase reporters
Cell Structure and FunctionStimulator of interferon genes (STING) triggers the type I interferon and inflammatory responses against a variety of DNA pathogens, which is essential to limiting viral infection and replication.
Tsumugi Shoji +8 more
doaj +1 more source
Heated Debates: Hot-Water Immersion or Ice Packs as First Aid for Cnidarian Envenomations?
Toxins, 2016 Cnidarian envenomations are an important public health problem, responsible for more deaths than shark attacks annually. For this reason, optimization of first-aid care is essential.
Christie L. Wilcox, Angel A. Yanagihara
doaj +1 more source
Advanced Functional Materials, EarlyView.PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu +14 more
wiley +1 more source
Toxins, 2017 Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to ...
Christie L. Wilcox +3 more
doaj +1 more source