Differential Phase Contrast Imaging to Predict MSC Immune Function
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui+5 more
wiley +1 more source
The human STING agonist E7766 induces immunogenic tumor clearance, independent of tumor-intrinsic STING expression in the <i>KRAS<sup>G12D/+</sup> Trp53<sup>-/-</sup></i> murine model of sarcoma. [PDF]
Hildebrand KM+8 more
europepmc +1 more source
Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang+6 more
wiley +1 more source
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier+3 more
wiley +1 more source
cGAS-STING Targeting Offers Novel Therapeutic Opportunities in Liver Diseases. [PDF]
Wang Y+8 more
europepmc +1 more source
Infantile multicystic encephalomalacia after maternal bee sting anaphylaxis during pregnancy [PDF]
Corrie E. Erasmus+2 more
openalex +1 more source
A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi+10 more
wiley +1 more source
Taking the STING out of neurodegenerative disease. [PDF]
Mangalmurti A, Lukens JR.
europepmc +1 more source
Treatment of Severe Anaphylactic Reactions to Insect Stings [PDF]
J F Ackroyd
openalex +1 more source
Retrospective Review on Reticular Materials: Facts and Figures Over the Last 30 Years
To shape the future course of research in reticular materials, this work reflects on the progress over the past 30 years, complemented by input from the community of 228 active researchers through a global, crowdsourced survey: ranging from demographics, how it works, publish and interact, to highlights on both academic and industrial milestones, as ...
Aamod V. Desai+8 more
wiley +1 more source