Results 81 to 90 of about 233,089 (385)

Sting jets in intense winter North-Atlantic windstorms [PDF]

open access: yes, 2012
Extratropical cyclones dominate autumn and winter weather over western Europe. The strongest cyclones, often termed windstorms, have a large socio-economic impact due to the strong surface winds and associated storm surges in coastal areas.
Arakawa A   +12 more
core   +1 more source

How the Innate Immune DNA Sensing cGAS-STING Pathway Is Involved in Apoptosis

open access: yesInternational Journal of Molecular Sciences, 2023
The cGAS–STING signaling axis can be activated by cytosolic DNA, including both non-self DNA and self DNA. This axis is used by the innate immune system to monitor invading pathogens and/or damage.
Wanglong Zheng   +5 more
semanticscholar   +1 more source

Sting fever [PDF]

open access: yesCurrent Biology, 2002
AbstractMediawatch: The arrival and spread of an exotic new disease in the eastern US has given the media opportunity to grab their readers and viewers during the traditionally slow news period of high summer. Richard F. Harris reports.
openaire   +1 more source

Understanding Contributors of Resilience in Youth With Childhood‐Onset Systemic Lupus Erythematosus Through a Socioecological Lens: A Mixed‐Methods Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino   +12 more
wiley   +1 more source

Social Services, School and the Climate of Civil Society

open access: yesSocial Work and Society, 2007
In an international perspective cooperation between social services and school has a long tradition. In the German speaking countries we can recognize a historical distance or gap between school and “social pedagogy”, but despite this tradition new ...
Stephan Sting
doaj  

Radiation unlocks the therapeutic potential of immune checkpoint blockers in lung cancer patients

open access: yesOncoImmunology, 2019
CTLA4 blockers have limited activity in patients with chemorefractory lung cancer. Recent clinical data demonstrate that radiation therapy combined with CTLA4 blockers enables disease control in a sizeable fraction of these patients, correlating with ...
Eric C. Ko, Lorenzo Galluzzi
doaj   +1 more source

Amplifying STING Activation by Cyclic Dinucleotide-Manganese Particles for Local and Systemic Cancer Metalloimmunotherapy

open access: yesNature Nanotechnology, 2021
Nutritional metal ions play critical roles in many important immune processes. Hence, the effective modulation of metal ions may open up new forms of immunotherapy, termed as metalloimmunotherapy.
Xiaoqi Sun   +12 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. [PDF]

open access: yes, 2018
Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially ...
Aliyari, Saba Roghiyh   +9 more
core  

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