Results 41 to 50 of about 1,142,003 (329)

The Effectiveness of the UNAIDS Strategy«90-90-90»in Populations with Different Population Growth

Эпидемиология и вакцинопрофилактика, 2020
Introduction. Available data indicate that the effectiveness of the strategy of "90-90-90" varies considerably between countries. For example, Australia with figures 90-90-79 (2016) has not achieved the negative trend of the incidence and prevalence ...
D. A. Neshumaev, E. N. Sukharev, V. L. Stasenko   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Precipitation Regulates the Assembly Processes of Rare Species in Phytoplankton Communities in River Ecosystems

Diversity
Phytoplankton communities typically comprise a few dominant species and numerous rare ones, but their responses to seasonal precipitation changes remain poorly understood.
Enze Xiao, Xiaofeng Liu, Tian Lou, Yimin Zhu, Yiou Wang, Xinxin Lu, Yawen Fan, Xiang Tan, Yan Liu   +8 more
doaj   +1 more source

Network Reliability Modeling Based on a Geometric Counting Process

Mathematics, 2018
In this paper, we investigate the reliability and stochastic properties of an n-component network under the assumption that the components of the network fail according to a counting process called a geometric counting process (GCP).
Somayeh Zarezadeh, Somayeh Ashrafi, Majid Asadi   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Improved susceptible–infectious–susceptible epidemic equations based on uncertainties and autocorrelation functions [PDF]

Royal Society Open Science, 2020
Compartmental equations are primary tools in the study of disease spreading processes. They provide accurate predictions for large populations but poor results whenever the integer nature of the number of agents is evident.
Gilberto M. Nakamura, George C. Cardoso, Alexandre S. Martinez   +2 more
doaj   +1 more source

Stochastic Light-Cone CTMRG: a new DMRG approach to stochastic models

, 2002
We develop a new variant of the recently introduced stochastic transfer-matrix DMRG which we call stochastic light-cone corner-transfer-matrix DMRG (LCTMRG).
A Gendiar, A Kemper, A Schadschneider, Bursill R J, de Oliveira S M, Enss T, Essam J W, GNU multiprecision library (GMP), J Zittartz, Kemper A, Kinzel W, Kinzel W, Marro J, Nishino T, Nishino T, Nishino T, Nishino T, Peschel I, Schütz G M, T Nishino, Trotter H F   +20 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source