Results 41 to 50 of about 198,332 (267)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Sensorless Speed Estimation of Induction Motors through Signal Analysis Based on Chaos Using Density of Maxima

Entropy
Three-phase induction motors are widely used in various industrial sectors and are responsible for a significant portion of the total electrical energy consumed.
Marlio Antonio Silva, Jose Anselmo Lucena-Junior, Julio Cesar da Silva, Francisco Antonio Belo, Abel Cavalcante Lima-Filho, Jorge Gabriel Gomes de Souza Ramos, Romulo Camara, Alisson Brito   +7 more
doaj   +1 more source

Characterization of Noise Signatures of Involuntary Head Motion in the Autism Brain Imaging Data Exchange Repository

Frontiers in Integrative Neuroscience, 2018
The variability inherently present in biophysical data is partly contributed by disparate sampling resolutions across instrumentations. This poses a potential problem for statistical inference using pooled data in open access repositories.
Carla Caballero, Sejal Mistry, Joe Vero, Elizabeth B Torres, Elizabeth B Torres, Elizabeth B Torres   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Economic Disposal Quantity of Leftovers kept in storage: a Monte Carlo simulation method

Open Engineering, 2019
This article describes how to reach an item’s threshold, or in other words, the limit time for it to be retrieved from stock and sold for a different use, as well as the remaining foreseen period for this situation to occur.
Assis R., Marques P. Carmona, Santos J. Oliveira, Vidal R.   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Pseudo-dynamic simulations applied to ball mill grinding circuit using population balance model and Monte Carlo Method [PDF]

REM: International Engineering Journal
Process simulations can be used to improve grinding circuit performance, which efficiently reduces operating costs. The population balance model (PBM) is widely accepted for grinding modeling because it can reproduce breakage events in tumbling mills, as
Jose Guilherme de Abreu Valadares, Douglas Batista Mazzinghy, Roberto Galéry   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Temperley Lieb stochastic processes [PDF]

Journal of Physics A: Mathematical and General, 2002
We discuss one-dimensional stochastic processes defined through the Temperley-Lieb algebra related to the Q=1 Potts model. For various boundary conditions, we formulate a conjecture relating the probability distribution which describes the stationary state, to the enumeration of a symmetry class of alternating sign matrices, objects that have received ...
Pearce, Paul A, Rittenberg, Vladimir, de Gier, J, Nienhuis, B   +3 more
openaire   +4 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source