Results 41 to 50 of about 11,390,317 (261)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Extremal behavior of stochastic volatility models [PDF]
Empirical volatility changes in time and exhibits tails, which are heavier than normal. Moreover, empirical volatility has - sometimes quite substantial - upwards jumps and clusters on high levels.
Lindner, Alexander M. +7 more
core +1 more source
Transforms of Stochastic Processes
In this note, the notion of an optimal transform of a (discrete parameter) stochastic process is introduced. Such transforms are shown to exist in certain cases, and a relationship to optimal stopping times is discussed. These ideas lead naturally to the representation of any given stochastic process as the transform of a submartingale.
openaire +3 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Combinatorial stochastic processes [PDF]
Well-known asymptotic results for sums of independent stochastic processes are extended to processes \(S = \sum^ n_{i = 1} \varphi_{i \pi (i)}\), where \(\varphi = (\varphi_{ij})_{1 \leq i,j \leq n}\) is a collection of independent stochastic processes \(\varphi_{ij}\) on some set \(\tau\), and \(\pi\) is a random permutation of \(\{1,2, \dots, n ...
openaire +2 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Densities for Stochastic Processes
Let $\{x_\theta(t), \theta \varepsilon \Omega\}$ be a family of stochastic processes defined by their finite dimensional distributions; that is, $\{F_\theta\lbrack x(t_1), \cdots, x(t_n)\rbrack; \theta \varepsilon \Omega\}$ is given for all finite sets of time points $t_1, \cdots, t_n$.
openaire +3 more sources
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Three-phase induction motors are widely used in various industrial sectors and are responsible for a significant portion of the total electrical energy consumed.
Marlio Antonio Silva +7 more
doaj +1 more source
The variability inherently present in biophysical data is partly contributed by disparate sampling resolutions across instrumentations. This poses a potential problem for statistical inference using pooled data in open access repositories.
Carla Caballero +5 more
doaj +1 more source

