Results 41 to 50 of about 5,790,115 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Quantifying scrambling in quantum neural networks
Journal of High Energy Physics, 2022 We quantify the role of scrambling in quantum machine learning. We characterize a quantum neural network’s (QNNs) error in terms of the network’s scrambling properties via the out-of-time-ordered correlator (OTOC).
Roy J. Garcia, Kaifeng Bu, Arthur Jaffe
doaj +1 more source
Combinatorial stochastic processes [PDF]
Stochastic Processes and their Applications, 1994 Well-known asymptotic results for sums of independent stochastic processes are extended to processes \(S = \sum^ n_{i = 1} \varphi_{i \pi (i)}\), where \(\varphi = (\varphi_{ij})_{1 \leq i,j \leq n}\) is a collection of independent stochastic processes \(\varphi_{ij}\) on some set \(\tau\), and \(\pi\) is a random permutation of \(\{1,2, \dots, n ...
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Communications, 2018 In this paper, we consider the robust adaptive non parametric estimation problem for the periodic function observed with the Levy noises in continuous time.
Evgeny Pchelintsev +2 more
doaj +1 more source
Barren plateaus from learning scramblers with local cost functions
Journal of High Energy Physics, 2023 The existence of barren plateaus has recently revealed new training challenges in quantum machine learning (QML). Uncovering the mechanisms behind barren plateaus is essential in understanding the scope of problems that QML can efficiently tackle. Barren
Roy J. Garcia +3 more
doaj +1 more source
The Past as a Stochastic Process
Journal of Computer Applications in Archaeology20 pages, 4 ...
David H. Wolpert +8 more
openaire +4 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Convergence of option rewards for Markov type price processes
, 2007 General condition of convergence are given for optimal rewards of American type options for perturbed Markopv type price processes controlled by market stochastic ...
Jonsson, H., +2 more
core +7 more sources