Results 51 to 60 of about 5,790,115 (297)

A comparative study of some exact designs for estimating the variance components

Kuwait Journal of Science
This study aims to investigate and compare several experimental designs for the efficient estimation of variance components. Some N-observation discrete/exact designs are to be considered for random effects models.
Zamzam Atash, Shahariar Huda, Meraou Mohammed Amine   +2 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Estimates for multiple stochastic integrals and stochastic Hamilton-Jacobi equations [PDF]

, 2004
We study stochastic Hamilton-Jacobi-Bellman equations and the corresponding Hamiltonian systems driven by jump-type Lévy processes. The main objective of the present paper is to show existence, uniqueness and a (locally in time) diffeomorphism ...
Kolokoltsov, V. N. (Vasiliĭ Nikitich), Tyukov, Alexei E., Schilling, René L., Vassili Kolokol'tsov, Alexei Tyukov, Schilling, RL, Tyukov, AE, Tyukov, A.E., Kolokoltsov, VN, Kolokol'tsov, V.N., René Schilling   +10 more
core   +1 more source

Existence of Measurable Versions of Stochastic Processes

Axioms
Let (X,A,P), (Y,B,Q) be two arbitrary probability spaces and P:={(A,Py):y∈Y} be a regular conditional probability (rcp) on A with respect to Q. Denote by R the skew product of P and Q determined by P on the product σ-algebra A⊗B and by R^ its completion.
Kazimierz Musiał
doaj   +1 more source

Temperley Lieb stochastic processes [PDF]

Journal of Physics A: Mathematical and General, 2002
We discuss one-dimensional stochastic processes defined through the Temperley-Lieb algebra related to the Q=1 Potts model. For various boundary conditions, we formulate a conjecture relating the probability distribution which describes the stationary state, to the enumeration of a symmetry class of alternating sign matrices, objects that have received ...
Pearce, Paul A, Rittenberg, Vladimir, de Gier, J, Nienhuis, B   +3 more
openaire   +4 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Quantum Conditional Stochastic Processes

Quanta
Quantum mechanics contains certain novel mathematical concepts. Among these are complex numbers, Hilbert spaces with their unitary and self-adjoint operators, states represented by complex vectors, superpositions of states, collapse of wave functions ...
Stan Gudder
doaj   +1 more source