Results 41 to 50 of about 30,771 (265)

Schemele de împădurire dese şi stabilitatea monoculturilor de molid – este posibilă realizarea unui echilibru de durată? [Narrow spacing and stability of Norway spruce monocultures - is a long-term equilibrium possible?] [PDF]

Bucovina Forestieră, 2003
Norway spruce (Picea abies (L.) Karst) - one of the most important forest species in both Europe (about 34 million ha) and Romania (about 1.4 million ha) - has been highly expanded in monocultures outside of its natural range since mid- 19th century.
Nicolescu N.-V, Petrițan I.-C, Vasilescu M.-M, Ferreira P, Henriques S   +4 more
doaj  

Modeling spatial variation in radiata pine slenderness (height/diameter ratio) and vulnerability to wind damage under current and future climate in New Zealand

Frontiers in Forests and Global Change, 2023
Wind is a significant disturbance agent in forests that is likely to become more prevalent as plantation forests are increasingly grown at high stand density to maximize yields and carbon sequestration.
Michael S. Watt, John R. Moore
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Loss of native brown trout diversity in streams of the continental Croatia

Frontiers in Environmental Science
Introduction: The genetic diversity of brown trout in the Western Balkans has been disrupted by the introduction of non-native Atlantic phylogenetic lineages and non-native haplotypes of the Danubian phylogenetic lineage.
Tamara Kanjuh, Ana Marić, Dubravka Škraba Jurlina, Predrag Simonović, Ivan Špelić, Marina Piria, Marina Piria, Ivana Maguire   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Combining population genomics and forward simulations to investigate stocking impacts: A case study of Muskellunge (Esox masquinongy) from the St. Lawrence River basin

Evolutionary Applications, 2019
Understanding the genetic and evolutionary impacts of stocking on wild fish populations has long been of interest as negative consequences such as reduced fitness and loss of genetic diversity are commonly reported outcomes.
Quentin Rougemont, Anne Carrier, Jeremy Le Luyer, Anne‐Laure Ferchaud, John M. Farrell, Daniel Hatin, Philippe Brodeur, Louis Bernatchez   +7 more
doaj   +1 more source

Physical, chemical and sensory evaluation of meat from cobia (rachycentron canadum), desensitized with different voltages of electric shock, stored under refrigeration

Ciência Rural, 2019
: Fish quality is conditioned by several factors, among them desensitization methods applied for fish managing and slaughtering. This research used electric shock at different intensities as a desensitization method for cobia (Rachycentron canadum ...
Fúlvio Viegas Santos Teixeira de Melo, Elisabete Maria Macedo Viegas, Giuliana Parisi, Adriana Cristina Bordignon, Manoel Adriano da Cruz Neto, Jose Fernando Bibiano Melo   +5 more
doaj   +1 more source