Results 121 to 130 of about 153,892 (355)
Pseudotyping exosomes for enhanced protein delivery in mammalian cells. [PDF]
, 2017 Exosomes are cell-derived nanovesicles that hold promise as living vehicles for intracellular delivery of therapeutics to mammalian cells. This potential, however, is undermined by the lack of effective methods to load exosomes with therapeutic proteins ...
Li, Lingxuan +5 more
core
Optimizing management of stage IV EGFR mutant non‐small cell lung cancer in Asia: An expert opinion
International Journal of Cancer, EarlyView.What's New? Emerging strategies for the treatment of advanced non‐small cell lung cancer (NSCLC) featuring epidermal growth factor receptor (EGFR) mutations are helping improve patient outcomes. Which strategies are optimal to effectively manage EGFR‐mutant NSCLC, however, remains unclear.
Gee‐Chen Chang +13 more
wiley +1 more source
Case Reports in Dermatology, 2020 We report a 23-year-old woman who presented with generalized scaly erythematous rash predominately on the upper trunk and hemorrhagic stomatitis. The histopathologic and immunopathologic findings were consistent with the diagnosis of paraneoplastic ...
Thirawut Sirikham +4 more
doaj +1 more source
Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors. [PDF]
, 2013 Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery ...
Hwang, B-Y, Schaffer, DV
core
International Journal of Cancer, EarlyView.What's New? Fluoropyrimidines, a key component of chemotherapy regimens for a variety of solid tumors, can cause severe toxicity. Patients who have specific genetic variants in the DPYD gene, which encodes an enzyme that inactivates fluoropyrimidines, have increased susceptibility to this toxicity.
Sofía L. J. Peeters +12 more
wiley +1 more source
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
The Journal of Clinical Pharmacology, EarlyView.Abstract Targeted therapies and immune checkpoint inhibitors (ICIs) have significantly improved survival outcomes in metastatic renal cell carcinoma (mRCC) but are often associated with high rates of adverse events, leading to dose reductions or treatment discontinuation.
Zhiyuan Tan +4 more
wiley +1 more source
Consilium MedicumUnfortunately, the occurrence of various pathologies in the ENT organs still remains one of the pressing problems in global healthcare. The frequent manifestation of unwanted pathologies forces us to change methods, and sometimes to introduce something ...
Sergey Ya. Kosyakov +2 more
doaj +1 more source
Recurrent aphthous stomatitis and Helicobacter pylori
Medicina Oral, 2016 Background Recurrent aphthous stomatitis (RAS) is a recurrent painful ulcerative disorder that commonly affects the oral mucosa. Local and systemic factors such as trauma, food sensitivity, nutritional deficiencies, systemic conditions, immunological ...
C. Gomes, R. Gomez, L. Zina, F. Amaral
semanticscholar +1 more source