Results 71 to 80 of about 153,892 (355)

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

Advanced Science, EarlyView.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang, Jiahui Zou, Yaoming Jin, Chenjun Jiang, Shaoyu Tu, Tong Chen, Jinli Guo, Yanqing Cheng, Meilin Jin, Huanchun Chen, Hongbo Zhou   +10 more
wiley   +1 more source

New approaches to therapy of oral inflammatory diseases [PDF]

Саратовский научно-медицинский журнал, 2013
The purpose of the work is to prescribe combined treatment in order to determine the efficiency of cycloferon liniment. Materials and methods. 80 patients suffering from such inflammatory disease of parodentium as herpetic stomatitis and periodontitis ...
Soboleva L.A., Bulkina N.V., Shuldyakov A.A., Pospelov A.N.   +3 more
doaj  

THE ROLE OF CANDIDA ALBICANS ON THE DEVELOPMENT OF STOMATITIS IN PATIENTS WEARING DENTURES

Sanamed, 2018
Denture stomatitis is the most common inflammatory reaction that occurs in people who wear dentures. It is believed that in 60-65% of cases the cause of this inflammation is infections by yeasts from the genus Candida (C.), primarily Candida albicans ...
Jovanovic Milica, Obradovic Radmila, Pejcic Ana, Stanisic Dragana, Stosic Nenad, Popovic Zana   +5 more
doaj   +1 more source

Oral mucosal injury caused by mammalian target of rapamycin inhibitors: emerging perspectives on pathobiology and impact on clinical practice. [PDF]

, 2016
In recent years oral mucosal injury has been increasingly recognized as an important toxicity associated with mammalian target of rapamycin (mTOR) inhibitors, including in patients with breast cancer who are receiving everolimus.
Campbell-Baird, Cynthia, Divers, Josephine, Elad, Sharon, Glaspy, John, Hronek, Jan, Meiller, Timothy F, O'Shaughnessy, Joyce A, Peterson, Douglas E, Rugo, Hope S, Schmidt, Brian L, Schubert, Mark M, Seery, Virginia, Viet, Chi T   +12 more
core  

A multicenter experience using adipose-derived mesenchymal stem cell therapy for cats with chronic, non-responsive gingivostomatitis. [PDF]

, 2020
BackgroundThe ability of mesenchymal stem cells (MSCs) to modulate immune responses inspired a series of clinical trials addressing oral mucosal inflammation.
Arzi, Boaz, Battig, Jean, Borjesson, Dori L, Clark, Kaitlin C, Delatorre, Ubaldo, Fiani, Nadine, Fulton, Amy, Lommer, Milinda J, Loscar, Megan R, Peralta, Santiago, Taechangam, Nopmanee, Vapniarsky, Natalia, Walker, Naomi J   +12 more
core   +1 more source

Everolimus plus exemestane in postmenopausal patients with HR(+) breast cancer: BOLERO-2 final progression-free survival analysis. [PDF]

, 2013
IntroductionEffective treatments for hormone-receptor-positive (HR(+)) breast cancer (BC) following relapse/progression on nonsteroidal aromatase inhibitor (NSAI) therapy are needed. Initial Breast Cancer Trials of OraL EveROlimus-2 (BOLERO-2) trial data
Arena, Francis P, Baselga, José, Burris, Howard A, Cahana, Ayelet, Campone, Mario, Erdkamp, Frans, Feng, Wentao, Gnant, Michael, Harb, Wael A, Hortobagyi, Gabriel N, Lebwohl, David, Melichar, Bohuslav, Noguchi, Shinzaburo, Petrakova, Katarina, Piccart, Martine, Pistilli, Barbara, Pritchard, Kathleen I, Rugo, Hope S, Taran, Tetiana, Yardley, Denise A   +19 more
core   +2 more sources

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source

Apthous ulcers: Its prevalence and distribution according to gender and site in different age groups-A descriptive study

The Saint's International Dental Journal, 2022
Objective: Recurrent aphthous ulcer, also known as aphthous stomatitis or canker sores, is the most common idiopathic in nature inflammatory disease of the oral mucosa, causing a great deal of pain and discomfort to the patient. The purpose of this study
Amit Kumar, Divya Kashyap
doaj   +1 more source

Efficacy of Camellia sinensis extract against Candida species in patients with denture stomatitis

Current Medical Mycology, 2018
Background and Purpose: Denture stomatitis is a chronic inflammation disease of the oral mucosa, which is specified by erythematous lesions mainly in the upper palate.
A. Ghorbani, Ashena Sadrzadeh, E. Habibi, Kosar Dadgar, J. Akbari, M. Moosazadeh, Bakhshi Hossein, F. Ahangarkani, A. Vaezi   +8 more
semanticscholar   +1 more source

Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity

Advanced Science, EarlyView.
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang, Yesheng Fu, Lihua Qiang, Mengyuan Zhao, Zhe Lu, Zhuo Zhao, Guoping Chen, Zehui Lei, Qiyao Chai, Pupu Ge, Bingxi Li, Jing Wang, Cui Hua Liu, Lingqiang Zhang   +13 more
wiley   +1 more source